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PIK-293 is a cell-permeable, selective inhibitor of the phosphatidylinositol 3-kinase (PI3K) catalytic subunit p110δ, with IC50s of 100, 25, 10, and 0.24 μM for p110 subunit isoforms α, β, γ, and δ, respectively. It serves as the parent compound for PIK-294 (P437705) and is a phosphoinositide 3-kinase delta (PI3Kδ) inhibitor.

900185-01-5

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900185-01-5 Usage

Uses

Used in Pharmaceutical Industry:
PIK-293 is used as a cancer therapy agent for its potential to inhibit the PI3Kδ enzyme, which plays a crucial role in various cellular processes and is implicated in the development and progression of cancer. The inhibition of PI3Kδ by PIK-293 shows promise in treating cancer, making it a valuable compound in the pharmaceutical industry for the development of targeted cancer therapies.

Check Digit Verification of cas no

The CAS Registry Mumber 900185-01-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,0,0,1,8 and 5 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 900185-01:
(8*9)+(7*0)+(6*0)+(5*1)+(4*8)+(3*5)+(2*0)+(1*1)=125
125 % 10 = 5
So 900185-01-5 is a valid CAS Registry Number.
InChI:InChI=1S/C22H19N7O/c1-13-6-3-4-9-17(13)29-18(27-16-8-5-7-14(2)19(16)22(29)30)11-28-21-15(10-26-28)20(23)24-12-25-21/h3-10,12H,11H2,1-2H3,(H2,23,24,25)

900185-01-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-[(4-aminopyrazolo[3,4-d]pyrimidin-1-yl)methyl]-5-methyl-3-(2-methylphenyl)quinazolin-4-one

1.2 Other means of identification

Product number -
Other names 2-((4-amino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl)-5-methyl-3-o-tolylquinazolin-4(3H)-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:900185-01-5 SDS

900185-01-5Downstream Products

900185-01-5Relevant academic research and scientific papers

METHODS AND COMPOSITIONS FOR TREATMENT OF OPHTHALMIC CONDITIONS

-

, (2011/11/12)

The present invention provides chemical entities or compounds and pharmaceutical compositions thereof that are capable of modulating signal transduction by certain protein kinases such as mTor, tyrosine kinases, and/or lipid kinases such as PB kinase in a

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