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9-(3-oxoprop-1-enyl)adenine, also known as 3-(6-Amino-9H-purin-9-yl)-2-propenal, is an endogenous compound that can form adducts with cellular DNA. It is considered one of the major sources of endogenous M1dG adducts in cellular DNA.

90029-73-5

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90029-73-5 Usage

Uses

Used in Research Applications:
9-(3-oxoprop-1-enyl)adenine is used as a research compound for studying the formation and repair of endogenous M1dG adducts in cellular DNA. Understanding the mechanisms of adduct formation and repair can help in developing strategies to prevent mutagenesis and carcinogenesis.
Used in Drug Development:
9-(3-oxoprop-1-enyl)adenine can be used as a target for drug development to design compounds that can inhibit its formation or promote its repair, thereby reducing the risk of mutagenesis and carcinogenesis.
Used in Cancer Prevention and Treatment:
9-(3-oxoprop-1-enyl)adenine can be used as a biomarker for early detection of cancer or as a target for cancer prevention and treatment strategies. By monitoring the levels of 9-(3-oxoprop-1-enyl)adenine in cellular DNA, it may be possible to identify individuals at higher risk of developing cancer and implement preventive measures. Additionally, targeting the repair of M1dG adducts may help in the development of novel therapeutic approaches for cancer treatment.

Check Digit Verification of cas no

The CAS Registry Mumber 90029-73-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,0,0,2 and 9 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 90029-73:
(7*9)+(6*0)+(5*0)+(4*2)+(3*9)+(2*7)+(1*3)=115
115 % 10 = 5
So 90029-73-5 is a valid CAS Registry Number.
InChI:InChI=1/C8H7N5O/c9-7-6-8(11-4-10-7)13(5-12-6)2-1-3-14/h1-5H,(H2,9,10,11)/b2-1+

90029-73-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name (E)-3-(6-aminopurin-9-yl)prop-2-enal

1.2 Other means of identification

Product number -
Other names Adenine propenal

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:90029-73-5 SDS

90029-73-5Downstream Products

90029-73-5Relevant academic research and scientific papers

Oxo propenyl nucleosides and nucleoside related analogs

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, (2008/06/13)

Certain 3-oxo-prop-1-enyl purine and pyrimidine derivatives and the corresponding nucleosides have been prepared. These compounds exhibit interesting and valuable cytotoxic activity. This cytotoxicity is of special interest in that it appears to inhibit DNA reproduction without affecting RNA or protein synthesis.

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