90040-41-8Relevant academic research and scientific papers
DIPHENYLHYDROXYMETHYLATION OF 2-METHYLPYRIDINE N-OXIDE BY KETYLS AND DIANIONS OF BENZOPHENONE
Kurbatova, A. S.,Kurbatov, Yu. V.,Niyazova, D. A.,Atayan, P. S.
, p. 168 - 170 (2007/10/02)
In the reaction of 2-methylpyridine N-oxide with the lithium ketyl and the dianion of benzophenone the products from diphenylhydroxymethylation in the side chain, i.e., 2-(1-hydroxy-1,1-diphenylethyl)pyridine N-oxide, and in the ring, i.e., 2-methyl-6-(diphenylhydroxymethyl)pyridine N-oxide, are formed.The product from reductive diphenylhydroxymethylation in the methyl group, i.e., 2-(1-hydroxy-1,1-diphenylethyl)pyridine, is formed preferentially in the reactions with the ketyl and the dianion of benzophenone.The condensation with the sodium ketyl and the dianion of benzophenone takes place similarly and leads to significantly lower yields of the products.
