90050-42-3

Basic information

• Product Name: N-(5-bromo-2-chloro-phenyl)-acetamide
• Synonyms: N-(5-bromo-2-chloro-phenyl)-acetamide
• CAS NO: 90050-42-3
• Molecular Weight: 248.507
• Mol File: 90050-42-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-(5-bromo-2-chloro-phenyl)-acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(5-bromo-2-chloro-phenyl)-acetamide(90050-42-3)
• EPA Substance Registry System: N-(5-bromo-2-chloro-phenyl)-acetamide(90050-42-3)

Safety Data

• Hazardous Substances Data: 90050-42-3(Hazardous Substances Data)

Upstream product

• 621-38-5 3-bromoacetanilide 
• 60811-17-8 5-bromo-2-chloroaniline 
• 108-24-7 acetic anhydride 
• 112160-74-4 acetic acid-(2,4,N-trichloro-anilide) 

Relevant articles and documents

Complementary Site-Selective Halogenation of Nitrogen-Containing (Hetero)Aromatics with Superacids

Site-selective functionalization of arenes that is complementary to classical aromatic substitution reactions remains a long-standing quest in organic synthesis. Exploiting the generation of halenium ion through oxidative process and the protonation of the nitrogen containing function in HF/SbF5, the chlorination and iodination of classically inert Csp2?H bonds of aromatic amines occurs. Furthermore, the superacid-promoted (poly)protonation of the molecules acts as a protection, favoring the late-stage selective halogenation of natural alkaloids and active pharmaceutical ingredients.

5-[(PIPERAZIN-1-YL)-3-OXO-PROPYL]-IMIDAZOLIDINE-2,4-DIONE DERIVATIVES AS ADAMTS INHIBITORS FOR THE TREATMENT OF OSTEOARTHRITIS

The present invention discloses compounds according to Formula (I), wherein R, R2, R3a, R3b, and Cy are as defined herein. The present invention discloses compounds inhibiting ADAMTS, methods for their production, pharmaceutical compositions comprising the same and methods for the prophylaxis and/or treatment of inflammatory conditions and/or diseases involving degradation of cartilage and/or disruption of cartilage homeostasis.