900519-35-9

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 900519-34-8 1-[(2S,5R,6R,8R,10R)-10-(tert-Butyl-dimethyl-silanyloxymethyl)-5-methyl-5-triethylsilanyloxy-1,7,9-trioxa-dispiro[5.1.5.2]pentadec-2-yl]-6-(4-methoxy-benzyloxy)-hexan-2-ol 
• 900519-32-6 2-[(2S,5R,6R,8R,10R)-10-(tert-Butyl-dimethyl-silanyloxymethyl)-5-methyl-5-triethylsilanyloxy-1,7,9-trioxa-dispiro[5.1.5.2]pentadec-2-yl]-ethanol 
• 900519-30-4 [(2R,6R,8R,10S,13R)-10-(2-Benzyloxy-ethyl)-13-methyl-13-triethylsilanyloxy-1,7,9-trioxa-dispiro[5.1.5.2]pentadec-2-yl]-methanol 
• 900519-33-7 [(2S,5R,6R,8R,10R)-10-(tert-Butyl-dimethyl-silanyloxymethyl)-5-methyl-5-triethylsilanyloxy-1,7,9-trioxa-dispiro[5.1.5.2]pentadec-2-yl]-acetaldehyde 

Downstream Products

• 900519-36-0 (2S,5R,6R,8R,10R)-10-(tert-Butyl-dimethyl-silanyloxymethyl)-2-[6-(4-methoxy-benzyloxy)-2-methylene-hexyl]-5-methyl-5-triethylsilanyloxy-1,7,9-trioxa-dispiro[5.1.5.2]pentadecane 
• 900519-39-3 {(2S,5R,6R,8R,10R)-10-[1,3]Dithian-2-ylmethyl-2-[6-(4-methoxy-benzyloxy)-2-methylene-hexyl]-5-methyl-1,7,9-trioxa-dispiro[5.1.5.2]pentadec-5-yloxy}-triethyl-silane 
• 900519-37-1 {(2R,6R,8R,10S,13R)-10-[6-(4-Methoxy-benzyloxy)-2-methylene-hexyl]-13-methyl-13-triethylsilanyloxy-1,7,9-trioxa-dispiro[5.1.5.2]pentadec-2-yl}-methanol 
• 900519-38-2 Triethyl-{(2S,5R,6R,8R,10R)-10-iodomethyl-2-[6-(4-methoxy-benzyloxy)-2-methylene-hexyl]-5-methyl-1,7,9-trioxa-dispiro[5.1.5.2]pentadec-5-yloxy}-silane 

Relevant academic research and scientific papers

Unified total synthesis of pteriatoxins and their diastereomers

A unified total synthesis is reported to access all of the possible diastereomers of pteriatoxins A-C, with the use of an intramolecular Diels-Alder reaction as the key step to form the carbo-macrocyclic core structure. The C34/C35-diol protecting groups were found to have significant effects on both the exo/endo-selectivity and the exo-facial selectivity of the intramolecular Diels-Alder process. Copyright