900521-60-0Relevant articles and documents
Synthesis of novel N-protected hydrophobic phenylalanines and their application in potential antibacterials
Boyle, Timothy P.,Bremner, John B.,Coates, Jonathan A.,Deadman, John,Keller, Paul A.,Pyne, Stephen G.,Somphol, Kittiya
, p. 1001 - 1009 (2009)
An efficient synthesis of two new N-acetyl-4′-arylphenylalanines is described together with their incorporation into a number of cationic peptoid antibacterial agents, one of which had an MIC of 7.8 μg/mL against Staphylococcus aureus. Crown Copyright
PEPTIDIC COMPOUNDS
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Page/Page column 173, (2008/06/13)
The present invention provides a compound of formula (I), (II), (III) and (IV) as defined herein and pharmaceutically acceptable derivatives thereof. The present invention further provides use of the compounds of the present invention in the treatment of bacterial infection and in the treatment of HIV infection. Also provided are pharmaceutical compositions comprising the compounds of the present invention.