90053-68-2Relevant articles and documents
Farnesylacetic acid ester derivatives
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, (2008/06/13)
Novel farnesylacetic acid ester derivatives containing an amine nitrogen in the alcohol residue thereof and represented by the following general formula exhibit high levels of antiulcerogenic activity and very low levels of toxicity: STR1 wherein A is an alkylene radical containing at least 2 carbon atoms; R1 is H, alkyl, cycloalkyl, aryl, aralkyl or alkenyl; R2 and R3 are independently H, alkyl, aryl, aralkyl or alkenyl or one of R2 and R3 forms, together with A, a piperidine, pyrrolidine, tetrahydropyrimidine or piperazine ring which contains the nitrogen atom lying therebetween or R2 and R3 combine to form, together with the adjacent nitrogen atom, a piperazine ring; provided that the total number of carbon atoms contained in A, R1, R2 and R3 is at least 5.