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Z-Ala-OMe, also known as Z-alaninol, is a synthetic peptide derivative that consists of a protected alanine residue with a methoxy group (OMe) at the N-terminus and a carbobenzyloxy (Z) group at the C-terminus. Z-Ala5-OMe is widely used in peptide synthesis as a building block, particularly in solid-phase peptide synthesis (SPPS) techniques. The Z group serves as a temporary protecting group for the α-amino group, preventing unwanted side reactions during the synthesis process, while the OMe group protects the α-hydroxyl group, allowing for controlled coupling and deprotection steps. Z-Ala-OMe is crucial for the formation of peptide bonds and plays a significant role in the development of pharmaceuticals, bioactive peptides, and other peptide-based compounds.

90058-01-8

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90058-01-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 90058-01-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,0,0,5 and 8 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 90058-01:
(7*9)+(6*0)+(5*0)+(4*5)+(3*8)+(2*0)+(1*1)=108
108 % 10 = 8
So 90058-01-8 is a valid CAS Registry Number.

90058-01-8Relevant academic research and scientific papers

Thermitase - A Thermostable Serine Protease. I. Synthesis of Alanine Peptide Esters as Substrates of the Enzyme

Jahreis, Guenther,Fittkau, Siegfried

, p. 35 - 40 (2007/10/02)

The synthesis of N-acetylated and N-succinylated peptide esters of alanine is described.The peptides are built up from the Z-protected peptides by liquid phase fragment condensation and by acylation of the deprotected peptide esters.The kinetic parameters Km and kcat of some compounds are presented.

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