90058-40-5

Basic information

• Product Name: Cyclobutanecarboxylic acid, 1-[[[[(phenylmethoxy)carbonyl]amino]acetyl]amino]-, methyl ester
• CAS NO: 90058-40-5
• Molecular Formula: C16H20N2O5
• Molecular Weight: 320.345
• Mol File: 90058-40-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Cyclobutanecarboxylic acid, 1-[[[[(phenylmethoxy)carbonyl]amino]acetyl]amino]-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclobutanecarboxylic acid, 1-[[[[(phenylmethoxy)carbonyl]amino]acetyl]amino]-, methyl ester(90058-40-5)
• EPA Substance Registry System: Cyclobutanecarboxylic acid, 1-[[[[(phenylmethoxy)carbonyl]amino]acetyl]amino]-, methyl ester(90058-40-5)

Safety Data

• Hazardous Substances Data: 90058-40-5(Hazardous Substances Data)

Upstream product

• 120728-10-1 1-[(tert-butoxycarbonyl)amino]cyclobutanecarboxylic acid 
• 1138-80-3 N-(Benzyloxycarbonyl)glycine 
• 92398-47-5 1-aminocyclobutane-1-carboxylic acid methyl ester hydrochloride 

Downstream Products

• 90058-41-6 cyclo(glycyl-1-amino-1-cyclobutanecarbonyl) 

Relevant articles and documents

UREA DERIVATIVES AS PYRUVATE KINASE ACTIVATORS

The subject matter described herein is directed to pyruvate kinase activating compounds of Formula I and pharmaceutical salts thereof, methods of preparing the compounds, pharmaceutical compositions comprising the compounds and methods of administering the compounds for the treatment of diseases associated with PKR and/or PKM2, such as pyruvate kinase deficiency, sickle cell disease, and beta-thalassemia.