900641-44-3

Usage

Uses

Used in Pharmaceutical Industry:
1-(4-Benzyl-piperazin-1-yl)-2-methylamino-ethanone is used as a chemical intermediate for the development of novel drugs and medications. Its unique structure, which includes a benzyl group and a methylamino group, allows for potential interactions with receptors in the central nervous system, making it a promising candidate for further research and development in the field of medicine and pharmacology.
Used in Research and Development:
1-(4-Benzyl-piperazin-1-yl)-2-methylamino-ethanone serves as a valuable compound for research purposes, particularly in the exploration of its biological activities and potential applications in medicine. Its structure and properties may provide insights into the development of new therapeutic strategies and contribute to the advancement of pharmaceutical science.

Upstream product

• 671212-35-4 tert-butyl ester of [2-(4-benzylpiperazin-1-yl)-2-oxoethyl]-N-methylcarbamic acid 
• 2759-28-6 1-phenylmethylpiperazine 

Downstream Products

• 1416064-43-1 C₂₆H₃₇N₃O₂ 

Relevant academic research and scientific papers

Inhibition of Ebola virus infection: Identification of niemann-pick C1 as the target by optimization of a chemical probe

A high-throughput screen identified adamantane dipeptide 1 as an inhibitor of Ebola virus (EboV) infection. Hit-to-lead optimization to determine the structure-activity relationship (SAR) identified the more potent EboV inhibitor 2 and a photoaffinity labeling agent 3. These antiviral compounds were employed to identify the target as Niemann-Pick C1 (NPC1), a host protein that binds the EboV glycoprotein and is essential for infection. These studies establish NPC1 as a promising target for antiviral therapy.

From tyrosine to glycine: Synthesis and biological activity of potent antagonists of the purinergic P2X7 receptor

The characterization of the native and recombinant P2X7 receptor continues to be hindered by the lack of specific and subtype-selective antagonists with a "druglike" profile. However, a tyrosine derivative named KN-62 exhibits selective P2Xsub