900796-17-0Relevant academic research and scientific papers
Synthesis and evaluation of N-aryl pyrrolidinones as novel anti-HIV-1 agents. Part 1
Wu, Baogen,Kuhen, Kelli,Ngoc Nguyen, Truc,Ellis, David,Anaclerio, Beth,He, Xiaohui,Yang, Kunyong,Karanewsky, Donald,Yin, Hong,Wolff, Karen,Bieza, Kimberly,Caldwell, Jeremy,He, Yun
, p. 3430 - 3433 (2006)
The synthesis and preliminary structure-activity relationship of a series of pyrrolidinones are described. These pyrrolidinones have been characterized as novel non-nucleoside reverse transcriptase inhibitors (NNRTIs) which are highly potent against wild-type and drug-resistant human immunodeficiency viruses (HIV-1).
