Intrinsic factor is a crucial glycoprotein secreted by the parietal cells in the stomach, which plays a vital role in the absorption of vitamin B12. It is essential for the proper functioning of the nervous system and the production of red blood cells. When vitamin B12 binds to intrinsic factor, it forms a complex that can be absorbed by the ileum in the small intestine. A deficiency in intrinsic factor, often due to pernicious anemia or surgical removal of the stomach, can lead to vitamin B12 deficiency, resulting in megaloblastic anemia and neurological disorders.
Synonyms: INTRINSIC FACTOR;INTRINSIC FACTOR (PORCINE);INTRINSIC FACTOR, PORCINE GASTRIC MUCOSA;intrinsic factor from porcine*gastric mucosa;intrinsic factor from rat stomach;IF, Vitamin B12-binding protein
The CAS Registry Mumber 9008-12-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 9,0,0 and 8 respectively; the second part has 2 digits, 1 and 2 respectively. Calculate Digit Verification of CAS Registry Number 9008-12: (6*9)+(5*0)+(4*0)+(3*8)+(2*1)+(1*2)=82 82 % 10 = 2 So 9008-12-2 is a valid CAS Registry Number.