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2-(1-amino-2-methylpropyl)-3-benzylthieno[2,3-d]pyrimidin-4(3H)-one is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

900809-18-9

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900809-18-9 Usage

Chemical class

Thienopyrimidinone derivatives

Target enzyme

Ataxia telangiectasia and Rad3-related (ATR) protein kinase

Biological role

Inhibition of ATR, which is involved in the DNA damage response pathway

Importance

ATR plays a crucial role in maintaining genome stability by detecting and repairing DNA damage

Potential application

Inhibition of ATR has potential applications in cancer therapy

Preclinical results

AG-14361 has shown promising results in preclinical studies for its ability to enhance the efficacy of chemotherapy and radiotherapy in cancer treatment

Unique feature

AG-14361 has a unique structure and selective inhibition of ATR, making it a valuable lead compound for the development of novel cancer therapeutics.

Check Digit Verification of cas no

The CAS Registry Mumber 900809-18-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,0,0,8,0 and 9 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 900809-18:
(8*9)+(7*0)+(6*0)+(5*8)+(4*0)+(3*9)+(2*1)+(1*8)=149
149 % 10 = 9
So 900809-18-9 is a valid CAS Registry Number.

900809-18-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(1-(R,S)-amino-2-methylpropyl)-3-benzylthieno[2,3-d]pyrimidin-4(3H)-one

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:900809-18-9 SDS

900809-18-9Relevant academic research and scientific papers

MITOTIC KINESIN INHIBITORS

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Page/Page column 46, (2008/06/13)

The present invention relates to fluorinated 2-aminomethylthienopyrimidinone compounds that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention

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