90083-79-7Relevant academic research and scientific papers
Usefully Functionalized Products from Conjugate Addition of Sulfur-Stabilized Anions to α-Enones
Myers, Michael R.,Cohen, Theodore
, p. 1290 - 1295 (2007/10/02)
The addition to α,β-unsaturated ketones of a variety of organolithiums stabilized by at least two phenylthio groups provides mainly the 1,4-addition products at low temperatures in the absence of complexing agents such as HMPA.The products thus generated
A Stereocontrolled Cyclopentenone Synthesis via Cycloaddition
Trost, Barry M.,Seoane, Peter,Mignani, Serge,Acemoglu, Murat
, p. 7487 - 7500 (2007/10/02)
γ-Alkoxy-α,β-unsaturated sulfones are readily available in both racemic and scalemic form, the latter either by asymmetric induction from achiral building block or from readily available scalemic starting materials.These electron deficient olefins serve as excellent substrates for cycloaddition involving the intermediacy of trimethylenemethane-palladium complexes.The highly diastereoselective methylenecyclopentannulation provides a versatile cycloadduct that allows very simple conversion to cyclopentenones and cyclopentadienes and the synthetic equivalent ofaddition to cycloalkanones and alkynones, two classes of substrate that either frequently give low yields or totally fail in palladium-catalyzed cycloadditions from 2-(acetoxymethyl)-3-(trimethylsilyl)prop-1-ene.
Metal-Catalyzed Stereospecific Michael Reaction Equivalent
Godleski, Stephen A.,Villhauer, Edwin B.
, p. 2246 - 2252 (2007/10/02)
The addition of nucleophiles to vinyl sulfide-allylic acetates mediated by (?-allyl)palladium intermediates has been shown to occur exclusively on the allyl terminus remote from sulfur, thereby effecting the equivalent to a Michael reaction.Due to the int
