90086-65-0 Usage
Structure
A cyclohexanol derivative with an ethynyl group attached to the carbon atom at position 1 and an iodine atom attached to the ethynyl group.
Organic synthesis
Used as a building block for the synthesis of various biologically active compounds.
Medicinal chemistry
Employed in the development of pharmaceuticals and drug candidates.
Precursor
Serves as a precursor for the preparation of other functionalized cyclohexanols and cyclohexanones.
Materials science
Has potential applications in the synthesis of novel organic materials with specific electronic and optical properties.
Cyclohexanol
A six-membered ring with an alcohol group (-OH) attached.
Ethynyl
A triple-bonded carbon chain (-C≡CH).
Iodine
A halogen atom (I) attached to the ethynyl group.
Reactivity
Due to the presence of the iodine atom and the triple bond in the ethynyl group, 1-(iodoethynyl)cyclohexanol can undergo various chemical reactions, such as substitution, addition, and elimination reactions.
Solubility
Likely soluble in organic solvents like dichloromethane, ethanol, and acetone, due to its nonpolar nature and the presence of the iodine atom.
Stability
May be sensitive to heat, light, and moisture, as it contains a reactive iodine atom and a triple bond. It should be stored in a cool, dark place and protected from moisture.
Hazards
Potential hazards may include toxicity, irritancy, and reactivity with other chemicals. It is essential to handle 1-(iodoethynyl)cyclohexanol with care and follow proper safety protocols.
Check Digit Verification of cas no
The CAS Registry Mumber 90086-65-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,0,0,8 and 6 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 90086-65:
(7*9)+(6*0)+(5*0)+(4*8)+(3*6)+(2*6)+(1*5)=130
130 % 10 = 0
So 90086-65-0 is a valid CAS Registry Number.
90086-65-0Relevant articles and documents
Method for preparing 1-halogenated alkyne under catalysis of heterogeneous Ag catalyst at room temperature
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Paragraph 0052; 0056, (2021/05/12)
The invention discloses a novel method for preparing 1-halogenated alkyne under the catalysis of a heterogeneous Ag catalyst at room temperature. The method comprises the steps of mixing terminal alkyne compounds containing different substituent groups, N
An alkynyliodide cycloaddition strategy for the construction of iodoisoxazoles
Crossley, James A.,Browne, Duncan L.
supporting information; scheme or table, p. 5414 - 5416 (2010/10/04)
(Figure presented) The thermally promoted cycloaddition between alkynyliodides and nitrile oxides is reported. The process offers excellent regioselectivity and a broad scope with respect to both the iodoalkynes and chloro-oximes. Further functionalization of the highly decorated iodoisoxazole motifs can be achieved via Suzuki cross-coupling.
β-Iodo Ketones by Prevost Reaction of Vinyl Carbinols
Ciganek, Engelbert,Calabrese, J. C.
, p. 4439 - 4443 (2007/10/02)
Treatment of α-ethenyl-α-phenylbenzenemethanol with iodine and silver acetate in either acetic acid or benzene gave 1,2-diphenyl-3-iodo-1-propanone (6) in 85percent yield.Ring enlargements involving similar rearrangements were observed with a number of cy
Copper(I)- and Phase Transfer-Catalysed Iodination of Terminal Alkynes
Jeffery, Tuyet
, p. 909 - 910 (2007/10/02)
A convenient synthesis of 1-iodoalk-1-ynes is reported, involving cooper(I)-catalysed iodination of terminal alkynes with molecular iodine under solid-liquid phase-transfer conditions.
