90086-89-8 Usage
Uses
Used in Pharmaceutical and Agrochemical Synthesis:
2-(Furan-2-yl)pyrrolidine is utilized as a key building block for the development of new pharmaceuticals and agrochemicals. Its presence in these compounds contributes to their unique properties and potential therapeutic or pesticidal effects.
Used in the Creation of Functional Materials:
Due to its structural features, 2-(Furan-2-yl)pyrrolidine is employed as a component in the design and synthesis of various functional materials, where its properties can be harnessed for specific applications.
Used as a Ligand in Metal-Catalyzed Reactions:
2-(Furan-2-yl)pyrrolidine has demonstrated its potential as a ligand in metal-catalyzed reactions, playing a crucial role in enhancing the efficiency and selectivity of these processes.
Used in Drug Discovery and Development:
2-(Furan-2-yl)pyrrolidine's interesting biological activities have made it a promising candidate for drug discovery and development, where it could be further optimized for therapeutic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 90086-89-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,0,0,8 and 6 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 90086-89:
(7*9)+(6*0)+(5*0)+(4*8)+(3*6)+(2*8)+(1*9)=138
138 % 10 = 8
So 90086-89-8 is a valid CAS Registry Number.
InChI:InChI=1/C8H11NO/c1-3-7(9-5-1)8-4-2-6-10-8/h2,4,6-7,9H,1,3,5H2
90086-89-8Relevant academic research and scientific papers
α-Functionalization of Cyclic Secondary Amines: Lewis Acid Promoted Addition of Organometallics to Transient Imines
Paul, Anirudra,Seidel, Daniel
supporting information, p. 8778 - 8782 (2019/06/07)
Cyclic imines, generated in situ from their corresponding N-lithiated amines and a ketone hydride acceptor, undergo reactions with a range of organometallic nucleophiles to generate α-functionalized amines in a single operation. Activation of the transient imines by Lewis acids that are compatible with the presence of lithium alkoxides was found to be crucial to accommodate a broad range of nucleophiles including lithium acetylides, Grignard reagents, and aryllithiums with attenuated reactivities.
A NOVEL THREE CARBON-AMINO GRIGNARD REAGENT: ITS USE IN AN EFFICIENT PYRROLIDINE SYNTHESIS
Basha, Fatima Z.,DeBernardis, John F.
, p. 5271 - 5274 (2007/10/02)
A novel primary amino protected Grignard reagent has been developed; 2,2,5,5-tetramethyl-1-aza-2,5-disilacyclopentane-1-propyl magnesium bromide 1a.Its usefulness is illustrated in the synthesis of 2-substituted pyrrolidines.
