901-90-6

Upstream product

• 76263-71-3 N-(3-methoxy-phenyl)-N-(toluene-4-sulfonyl)-β-alanine 
• 412337-55-4 3-[(3-Methoxy-phenyl)-(toluene-4-sulfonyl)-amino]-propionyl chloride 
• 536-90-3 m-Anisidine 
• 75227-24-6 ethyl 3-(3-methoxyphenylamino)propionate 

Downstream Products

• 76263-66-6 (E)-3-benzylidene-7-methoxy-1-tosyl-2,3-dihydroquinolin-4(1H)-one 
• 76263-67-7 7-Methoxy-3-[1-(4-methoxy-phenyl)-meth-(E)-ylidene]-1-(toluene-4-sulfonyl)-2,3-dihydro-1H-quinolin-4-one 
• 75227-42-8 3-[1-Hydroxy-meth-(E)-ylidene]-7-methoxy-1-(toluene-4-sulfonyl)-2,3-dihydro-1H-quinolin-4-one 
• 200010-37-3 7-Methoxy-4-methylene-1-(toluene-4-sulfonyl)-1,2,3,4-tetrahydro-quinoline 
• 76263-69-9 1-[(3S,3aR)-7-Methoxy-3-phenyl-5-(toluene-4-sulfonyl)-3,3a,4,5-tetrahydro-pyrazolo[4,3-c]quinolin-2-yl]-ethanone 
• 76263-70-2 1-[(3S,3aR)-7-Methoxy-3-(4-methoxy-phenyl)-5-(toluene-4-sulfonyl)-3,3a,4,5-tetrahydro-pyrazolo[4,3-c]quinolin-2-yl]-ethanone 
• 103687-98-5 1,4-bis(1,2,3,4-tetrahydro-7-methoxy-4-oxo-1-tosyl-3-quinolinylidenemethyl)piperazine 
• 103688-01-3 7-methoxy-2-phenyl-5-tosyl-4,5-dihydro-2H-pyrazolo[4,3-c]quinoline 
• 103688-07-9 7-Methoxy-2-phenyl-2H-pyrazolo[4,3-c]quinoline 
• 200010-42-0 8-Methoxy-1-(toluene-4-sulfonyl)-1,2,3,5-tetrahydro-benzo[b]azepin-4-one oxime 
• 200010-38-4 8-Methoxy-1-(toluene-4-sulfonyl)-1,2,3,5-tetrahydro-benzo[b]azepin-4-one 

Relevant academic research and scientific papers

Azabenzocycloheptenones. Part 20. Synthesis and utilisation of 4-amino-1,2,3,4-tetrahydro-1(1H)-benzazepines

1,2,3,4-Tetrahydro-6- and -7-methoxy-4-oxo-1-(p-tolylsulfonyl)quinolines 3 (R = tosyl, X = 6- and 7-OMe) and 1-ethoxycarbonylmethyl-1,2,3,4-tetrahydro-7-methoxy-4-oxoquinoline3 (R = CH2CO2Et, X = 7-OMe) have been ring-expanded in two

Studies in Antifertility Agents: Part XXVII - Synthesis of 2-Acetyl-3-aryl-5-tosyl-7/8-H (or methoxy)-3,3a,4,5-tetrahydropyrazoloquinolines

N-Tosyl-2,3-dihydro-4-quinolones (12-14), prepared from aniline, m- and p-anisidines by reported procedures, on condensation with araldehydes in the presence of NaOMe give the corresponding 3-arylidene-4-quinolones (15-18).Refluxing of 15-18 with NH2-NH2*H2O in gl.AcOH affords the title compounds, 2-acetyl-3-aryl-5-tosyl-7/8-H (or methoxy)-3,3a,4,5-tetrahydropyrazoloquinolines (19-22).The stereochemistry of the title compounds based on the assignments of C3-H, C3a-H, C4-H2 protons has been studied by PMR decoupling experiments.In preliminary screening, compounds 19 and 22 have been found to prevent pregnancy at 20 mg/kg dose in female albino rats, but are ineffective at lower doses.None of the compounds tested shows any significant pharmacological activity.