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Zabiciprilat, also known as LCI699, is a novel dual inhibitor of the enzymes neprilysin and angiotensin-converting enzyme (ACE), which plays a significant role in the regulation of blood pressure and fluid balance in the body. It is designed to simultaneously target two key pathways involved in heart failure, hypertension, and other cardiovascular conditions. By inhibiting neprilysin, zabiciprilat helps to increase levels of natriuretic peptides, which promote vasodilation, diuresis, and natriuresis, while also reducing the breakdown of angiotensin II, a potent vasoconstrictor. This dual mechanism of action aims to provide a more comprehensive approach to managing cardiovascular diseases compared to traditional single-target therapies. Clinical trials are ongoing to evaluate the safety and efficacy of zabiciprilat in various patient populations.

90103-92-7

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90103-92-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 90103-92-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,0,1,0 and 3 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 90103-92:
(7*9)+(6*0)+(5*1)+(4*0)+(3*3)+(2*9)+(1*2)=97
97 % 10 = 7
So 90103-92-7 is a valid CAS Registry Number.
InChI:InChI=1/C21H28N2O5/c1-13(22-17(20(25)26)12-7-14-5-3-2-4-6-14)19(24)23-16-10-8-15(9-11-16)18(23)21(27)28/h2-6,13,15-18,22H,7-12H2,1H3,(H,25,26)(H,27,28)/t13-,15?,16?,17-,18-/m0/s1

90103-92-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name (2S)-3-[(2S)-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]propanoyl]-3-azabicyclo[2.2.2]octane-2-carboxylic acid

1.2 Other means of identification

Product number -
Other names Zabiciprilate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:90103-92-7 SDS

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