90105-49-0Relevant academic research and scientific papers
Stereoselective Reduction of Prochiral Cyclic 1,3-Diketones Using Different Biocatalysts
Contente, Martina Letizia,Dall’Oglio, Federica,Annunziata, Francesca,Molinari, Francesco,Rabuffetti, Marco,Romano, Diego,Tamborini, Lucia,Rother, D?rte,Pinto, Andrea
, p. 1176 - 1185 (2019/11/16)
We have developed biocatalytic methods for the stereoselective reduction of cyclic prochiral 1,3-diketones for the production of optically active β-hydroxyketones and/or 1,3-diols. The recombinant ketoreductase KRED1-Pglu (formulated as purified catalyst)
Enantioselective desymmetrizing palladium catalyzed carbonylation reactions: The catalytic asymmetric synthesis of quaternary carbon center containing 1,3-dienes
Byrne, Simon J.,Fletcher, Anthony J.,Hebeisen, Paul,Willis, Michael C.
supporting information; experimental part, p. 758 - 760 (2010/06/20)
A desymmetrization protocol has been used to develop a palladium catalyzed enantioselective carbonylation process. Achiral cyclic bis-alkenyltriflates are converted to their corresponding monoester derivatives with selectivities of up to 96% ee. The Royal
Comparative reductive desymmetrization of 2,2-disubstituted-cycloalkane-1,3-diones
Carr, Jeremy M.,Snowden, Timothy S.
, p. 2897 - 2905 (2008/09/20)
Reductive desymmetrization of 2-methyl-2-substituted-cycloalkane-1,3-diones can be effected using either NaBH4 in DME or lithium tri-tert-butoxyaluminum hydride (LTBA) in THF at -60 °C. The former is a new approach that offers slightly greater
Poly(ethylene glycol) (400) as superior solvent medium against ionic liquids for catalytic hydrogenations with PtO2
Chandrasekhar, Srivari,Prakash, Samala Jaya,Rao, Chennamaneni Lohitha
, p. 2196 - 2199 (2007/10/03)
Adams' catalyst in poly(ethylene glycol) (PEG) (400) has been found to be a superior solvent over the ionic liquids by severalfold in promoting the hydrogenation of various functional groups. Both the catalyst and PEG were recycled efficiently over 10 runs without loss of activity, and substrate cross contamination was not observed despite a change in the substrate four times.
Asymmetric Microbial Reduction of Prochiral 2,2-Disubstituted Cycloalkanediones
Brooks, Dee W.,Mazdiyasni, Hormoz,Grothaus, Paul G.
, p. 3223 - 3232 (2007/10/02)
Asymmetric microbial reduction of a series of 2,2-disubstituted 1,3-cycloalkanediones with bakers' yeast was examined as an example of an enzyme-catalyzed distinction of a substrate containing two trigonal carbonyl centers with stereoheterotropic faces an
CHIRAL CYCLOHEXANOID SYNTHETIC PRECURSORS VIA ASYMMETRIC MICROBIAL REDUCTION OF PROCHIRAL CYCLOHEXANEDIONES
Brooks, Dee W.,Mazdiyasni, Hormoz,Chakrabarti, Sharmistha
, p. 1241 - 1244 (2007/10/02)
Microbial reduction of various 2,2-disubstituted-1,3-cyclohexanediones with bakers' yeast provides efficient access to chiral cyclohexanoid synthetic precursors.
