90109-15-2Relevant academic research and scientific papers
Catechol derivatives of 6-aminobenzocycloheptene: Assessment of dopaminergic effects
Cannon,Pease,Long,Flynn
, p. 922 - 923 (1984)
The title compounds were prepared as congeners of the dopaminergically potent 2-amino-5,6-dihydroxytetralin series ('A-5,6-DTN'). None of the variously nitrogen-substituted benzocycloheptenes demonstrated any dopamine-like effects in a variety of assays. The primary amine had α1-adrenoceptor stimulant effects. This lack of dopaminergic effect parallels the inactivity found in 6-aminobenzocycloheptenes bearing no oxygen substitutents, those bearing a single phenolic group, and those bearing a resorcinol 13-diphenolic substitution pattern.
