90111-15-2

Basic information

• Product Name: 3-hydroxy-2-methylbenzaldehyde
• Synonyms: 3-hydroxy-2-methylbenzaldehyde;Benzaldehyde, 3-hydroxy-2-Methyl-;2-methyl-3-oxidanyl-benzaldehyde;3,2-Cresotaldehyde
• CAS NO: 90111-15-2
• Molecular Formula: C₈H₈O₂
• Molecular Weight: 136.14792
• Mol File: 90111-15-2.mol

Chemical Properties

• Boiling Point: 250.6 °C at 760 mmHg
• Flash Point: 103.3 °C
• Appearance: /
• Density: 1.175 g/cm³
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 9.59±0.10(Predicted)
• CAS DataBase Reference: 3-hydroxy-2-methylbenzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 3-hydroxy-2-methylbenzaldehyde(90111-15-2)
• EPA Substance Registry System: 3-hydroxy-2-methylbenzaldehyde(90111-15-2)

Safety Data

• Hazardous Substances Data: 90111-15-2(Hazardous Substances Data)

Usage

Uses

Used in Fragrance Industry:
3-hydroxy-2-methylbenzaldehyde is used as a key ingredient in the production of perfumes for its sweet, floral scent, enhancing the overall fragrance profile of various products.
Used in Flavoring Industry:
It is utilized as a flavoring agent in food products, imparting a unique taste and aroma that contributes to the sensory experience of consumables.
Used in Cosmetics Industry:
3-hydroxy-2-methylbenzaldehyde is employed in the formulation of cosmetics, where its pleasant aroma adds to the appeal and consumer acceptance of these products.
Used in Medical Research:
This chemical is studied for its potential anti-inflammatory and antioxidant properties, indicating possible applications in the development of pharmaceuticals and therapeutic agents.

Upstream product

• 529-20-4 2-methylphenyl aldehyde 
• 7218-20-4 (RS)-6-Acetoxy-5,6-dimethyl-2,4-cyclohexadien-1-on 

Downstream Products

• 928716-10-3 3-ethoxy-2-methylbenzaldehyde 
• 56724-03-9 3-methoxy-2-methyl-benzaldehyde 

Relevant articles and documents

Pd-Catalyzed Ortho C-H Hydroxylation of Benzaldehydes Using a Transient Directing Group

The direct Pd-catalyzed ortho C-H hydroxylation of benzaldehydes was achieved using 4-chloroanthranilic acid as the transient directing group, 1-fluoro-2,4,6-trimethylpyridnium triflate as the bystanding oxidant, and p-toluenesulfonic acid as the putative oxygen nucleophile. The unusual C-H chlorination and polyfluoroalkoxylation reactions signaled the importance of external nucleophiles to the outcome of Pd(IV) reductive eliminations.

Phenylglycine derivatives useful for treating disorders of the central nervous system

A pharmaceutical compound of the formula: STR1 in which R1 is hydrogen, hydroxy or C1-6 alkoxy, R2 is hydrogen, carboxy, tetrazolyl, --SO2 H, --SO3 H, --OSO3 H, --CONHOH, or --P(OH)OR', --PO(OH)OR', --OP(OH)OR' or --OPO(OH)OR' where R' is hydrogen, C1-6 alkyl, C2-6 alkenyl or aryl C1-6 alkyl, R3 is hydrogen, hydroxy or C1-4 alkoxy, and R4 is fluoro, trifluoromethyl, nitro, C1-6 alkyl, C3-7 cycloalkyl, C2-6 alkenyl, C2-6 alkynyl, C1-6 alkylthio, heteroaryl, optionally substituted aryl, optionally substituted aryl C1-6 alkyl, optionally substituted aryl C2-6 alkenyl, optionally substituted aryl C2-6 alkynyl, optionally substituted aryloxy, optionally substituted aryl C1-6 alkoxy, optionally substituted arylthio, optionally substituted aryl C1-6 alkylthio or --CONR"R'", --SO2 NR"R"", --NR"R'", --OCONR"R"' or --SONR"R'" where R" and R'" are each hydrogen, C1-6 alkyl or aryl C1-6 alkyl, or R" and R'" together form a C3-7 alkylene ring; provided that (i) R1, R2 and R3 are not all hydrogen,and (ii) when R2 and R3 are hydrogen and R1 is hydroxy, R4 is not fluoro; or a salt or ester thereof.