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Penicillinase, also known as beta-lactamase, is an enzyme produced by certain bacteria that provides resistance to penicillin and other beta-lactam antibiotics. It functions by cleaving the beta-lactam ring in the antibiotic molecule, which inactivates the antibiotic. This enzymatic activity enables bacteria to survive and proliferate even in the presence of penicillin, leading to antibiotic resistance. Penicillinase is a key factor in the development of antibiotic resistance, presenting a considerable challenge in managing bacterial infections. Strategies to counteract this resistance include the invention of novel antibiotics and the application of beta-lactamase inhibitors to neutralize the effects of penicillinase.

9012-26-4

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9012-26-4 Usage

Uses

Used in Medical Research:
Penicillinase is utilized as a research tool for studying antibiotic resistance mechanisms in bacteria. Understanding how penicillinase confers resistance helps in the development of new antibiotics and strategies to overcome resistance.
Used in Pharmaceutical Development:
Penicillinase is employed in the development of beta-lactamase inhibitors, which are co-administered with beta-lactam antibiotics to protect them from enzymatic degradation. This combination therapy aims to enhance the effectiveness of antibiotics against resistant bacteria.
Used in Diagnostics:
Penicillinase can be used in diagnostic tests to identify the presence of beta-lactamase-producing bacteria in clinical samples. This information is crucial for guiding appropriate antibiotic therapy and managing infections effectively.
Used in Antibiotic Stewardship Programs:
Penicillinase plays a role in antibiotic stewardship programs by informing the selection of appropriate antibiotics for treatment. By understanding the mechanisms of resistance, healthcare providers can make more informed decisions about which antibiotics to use, reducing the spread of antibiotic resistance.
Used in Agricultural Applications:
In veterinary medicine and agriculture, penicillinase is considered in the development of strategies to manage antibiotic resistance in livestock and crops. This includes the prudent use of antibiotics and the development of alternative treatments to minimize the emergence of resistant bacterial strains.

Check Digit Verification of cas no

The CAS Registry Mumber 9012-26-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 9,0,1 and 2 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 9012-26:
(6*9)+(5*0)+(4*1)+(3*2)+(2*2)+(1*6)=74
74 % 10 = 4
So 9012-26-4 is a valid CAS Registry Number.

9012-26-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name Cephalosporinase from Bacillus (1×106units/vial)

1.2 Other means of identification

Product number -
Other names 2,7,12-Triiodo-5,5,10,10,15,15-hexamethyl-10,15-dihydro-5-diindeno[1,2-:1',2'-]fluorene

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:9012-26-4 SDS

9012-26-4Upstream product

9012-26-4Downstream Products

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