Aspartate transcarbamoylase from Streptococcus faecalis is a crucial enzyme involved in the biosynthesis of pyrimidine nucleotides, specifically playing a role in the first step of the pathway. This enzyme catalyzes the reaction between aspartate and carbamoyl phosphate to form phosphoribosyl carbamate, which is a key intermediate in the synthesis of both cytosine and thymine nucleotides. The enzyme is a homotrimer, consisting of three identical subunits, and is known for its allosteric regulation, which allows it to respond to changes in the cellular environment, particularly the levels of ATP and CTP. This regulation is important for controlling the rate of pyrimidine synthesis in accordance with the cell's needs.
The CAS Registry Mumber 9012-49-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 9,0,1 and 2 respectively; the second part has 2 digits, 4 and 9 respectively. Calculate Digit Verification of CAS Registry Number 9012-49: (6*9)+(5*0)+(4*1)+(3*2)+(2*4)+(1*9)=81 81 % 10 = 1 So 9012-49-1 is a valid CAS Registry Number.
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