Choline acetyltransferase (ChAT) is an enzyme found in human placenta, which plays a crucial role in the synthesis of the neurotransmitter acetylcholine. This enzyme catalyzes the transfer of an acetyl group from acetyl-CoA to choline, resulting in the formation of acetylcholine. Acetylcholine is essential for various physiological processes, including muscle contraction, memory, and learning. ChAT is highly expressed in the nervous system, particularly in the cholinergic neurons, and its activity is critical for maintaining proper neurotransmission. In the human placenta, ChAT is involved in the transfer of nutrients and signaling molecules from the mother to the fetus, ensuring proper fetal development. Any alterations in ChAT activity or expression can lead to various neurological disorders, highlighting the importance of understanding and studying this enzyme.
The CAS Registry Mumber 9012-78-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 9,0,1 and 2 respectively; the second part has 2 digits, 7 and 8 respectively. Calculate Digit Verification of CAS Registry Number 9012-78: (6*9)+(5*0)+(4*1)+(3*2)+(2*7)+(1*8)=86 86 % 10 = 6 So 9012-78-6 is a valid CAS Registry Number.
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