90141-11-0Relevant academic research and scientific papers
Haval-Argade contrathermodynamic rearrangement of alkylidenesuccinimides to alkylmaleimides via the corresponding isoimides: A general approach to alkyl and dialkyl substituted maleimides
Haval, Kishan P.,Argade, Narshinha P.
, p. 3557 - 3563 (2007/10/03)
A simple and efficient access to alkyl and dialkyl substituted maleimides has been demonstrated via the new contrathermodynamic rearrangement of (E)-alkylidenesuccinimides to alkylmaleimides. The (E)-alkylidenesuccinimides obtained from the Wittig-condens
Cyanuric chloride: Decent dehydrating agent for an exclusive and efficient synthesis of kinetically controlled isomaleimides
Haval, Kishan P.,Mhaske, Santosh B.,Argade, Narshinha P.
, p. 937 - 942 (2007/10/03)
Starting from maleanilic and maleamic acids, a facile general approach to kinetically controlled isomaleimides has been described for the first time using cyanuric chloride as a dehydrating agent with 85-98% yields. The effect of a variety of substituents
Reaction Mechanism between Pyruvic Acid and Aromatic Amines
Tapia, I.,Alcazar, V.,Moran, J. R.,Grande, M.
, p. 2408 - 2413 (2007/10/02)
The formation of the condensation products obtained when pyruvic acid and aromatic amines are allowed to react, can be explained by condensation of one mole of the imine of pyruvic acid with one mole of the enamine isomer, either through the C-atom or through the N-atom, followed by elimination and lactonization to give a γ-lactone carboxylate or an azlactone carboxylate, which on decarboxylation give an iminobutanolide or an azlactone respectively.Aminolysis of these cyclic intermediates led to the formation of the final products.
