90155-57-0Relevant academic research and scientific papers
Evaluation of malonic acid diamide analogues as radical scavenging agents
Patil, Ajay B.,Ghosh, Sougata,Phadatare, Suvarna D.,Pathak, Priyanath,Sharma, Geeta K.,Chopade, Balu A.,Shinde, Vaishali S.
, p. 1267 - 1273 (2015/02/19)
The malonic acid diamide analogues such as N,N′-dimethyl-N,N′-dioctyl-malonamide (DMDOMA), N,N′-dimethyl-N,N′-dioctyl-2,(2′-hexyloxyethyl) malonamide (DMDOHEMA), N,N′-dimethyl-N,N′-dicyclohexyl-malonamide (DMDCMA) and N,N,N′,N′-tetraisopropyl malonamide (TiPMA) were synthesized by an ester amine coupling method. These synthesized diamides were evaluated for the scavenging activity of the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical, superoxide anion scavenging and ferric reducing antioxidant power (FRAP), by biochemical methods. Antioxidant properties exhibited by these diamides were compared with standard antioxidants like gallic acid and ascorbic acid. The pulse radiolysis technique was employed to generate 2-2′-azinobis 3-ethylbenzothioline-6-sulfonic acid (ABTS+), hydroxyl radicals (OH), and carbonate (CO3-) radicals for evaluating the scavenging activity of the diamides. DMDCMA, TiPMA, and DMDOMA were found to show better antioxidant potential as compared to DMDOHEMA due to their more hydrophilic nature. The pulse radiolysis technique was found to be advantageous for investigating the interaction of the diamide class of compounds with radicals generated under high energy radiation.
Rational design of superoxide dismutase (sod) mimics: The evaluation of the therapeutic potential of new cationic Mn porphyrins with linear and cyclic substituents
Tovmasyan, Artak,Carballal, Sebastian,Ghazaryan, Robert,Melikyan, Lida,Weitner, Tin,Maia, Clarissa G. C.,Reboucas, Julio S.,Radi, Rafael,Spasojevic, Ivan,Benov, Ludmil,Batinic-Haberle, Ines
, p. 11467 - 11483 (2015/01/16)
Our goal herein has been to gain further insight into the parameters which control porphyrin therapeutic potential. Mn porphyrins (MnTnOct-2-PyP5+, MnTnHexOE-2-PyP5+, MnTE-2-PyPhP5+, and MnTPhE-2-PyP5+) that bea
ANTIMICROBIAL POLYETHER AND POLYOL COMPOUNDS
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Page/Page column 104-105, (2012/05/05)
The present application describes compounds of Formula I and Formula IA and as disclosed herein, that are useful as anti-microbial agents, including as antibacterial, disinfectant, antifungal, germicidal or antiviral agents.
A Synthesis of acetamidines
Harjani, Jitendra R.,Liang, Chen,Jessop, Philip G.
experimental part, p. 1683 - 1691 (2011/05/12)
The condensation of primary amine with N,N-dimethylacetamide dimethyl acetal yields amixture of acetamidine and imidate ester. The product distribution in this reaction depends on the temperature, solvent, and structure of the primary amine. It is possible to suppress the formation of imidate ester by performing the reaction in the presence of excess dimethyl amine, yielding acetamidine as the exclusive product. For acetamidines that cannot be purified either by crystallization or distillation, this new method is necessary for the generation of pure acetamidines in good yields.
