901568-85-2

Basic information

• Product Name: methyl 2-(5-oxo-1-phenyl-4-(3,4,5-trimethoxybenzylidene)-4,5-dihydro-1H-pyrazol-3-yl)acetate
• CAS NO: 901568-85-2
• Molecular Weight: 410.426
• Mol File: 901568-85-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 2-(5-oxo-1-phenyl-4-(3,4,5-trimethoxybenzylidene)-4,5-dihydro-1H-pyrazol-3-yl)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-(5-oxo-1-phenyl-4-(3,4,5-trimethoxybenzylidene)-4,5-dihydro-1H-pyrazol-3-yl)acetate(901568-85-2)
• EPA Substance Registry System: methyl 2-(5-oxo-1-phenyl-4-(3,4,5-trimethoxybenzylidene)-4,5-dihydro-1H-pyrazol-3-yl)acetate(901568-85-2)

Safety Data

• Hazardous Substances Data: 901568-85-2(Hazardous Substances Data)

Upstream product

• 105041-27-8 (5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-3-yl)-acetic acid methyl ester 
• 86-81-7 3,4,5-trimethoxy-benzaldehyde 

Relevant articles and documents

Detour of prenostodione synthesis towards pyrazolones for antibacterial activity

Our attempts to prepare indolyl acid (3), enroute to prenostodione (2), from phenyl-hydrazine following a reported procedure of Fischer-Indole synthesis rather lead to ethyl 2-(5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-3-yl)acetate as a major product, which underwent facile condensation with aldehydes to provide the pyrazolones. Intrigued by the opportunity for the diversity oriented synthesis of substituted pyrazolones, we have developed a facile one pot approach for pyrazolones and screened for antibacterial activity and, herein, results are reported.