90158-59-1Relevant academic research and scientific papers
Dibenzoxazepine compounds useful in the treatment of cerebral vasospasm or its sequela
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, (2008/06/13)
Disclosed is a therapeutic agent for the treatment of peripheral circulatory disorders that contains as the effective ingredient a dibenzoxazepin derivative of the following formula or a pharmaceutically acceptable salt thereof: STR1 where R1 is a hydrogen atom, a halogen atom, a lower alkyl group or a lower alkoxy group; R2 is a hydrogen atom or a lower alkyl group; and A signifies the group STR2 (where R3 is a hydrogen atom, a lower alkyl group, an optionally substituted phenyl group or a styryl group). Also, disclosed is a method for treatment of peripheral circulatory disorders by administering the compound of the formula (I) or a pharmaceutically acceptable salt thereof to a patient suffering from such disorders.
Dibenzoxazepine derivative, and pharmaceutical composition comprising the same
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, (2008/06/13)
Dibenzoxazepine derivatives of the formula: STR1 wherein R1, n, R2 and R3 are as defined in the description, process for preparing the same, pharmaceutical composition containing the same and method of treating diseases in circulatory organs administering the composition to a patient are disclosed. The compounds of the formula have lipid lowering activity, lipid peroxide lowering activity, blood sugar lowering activity and activity to inhibit the aggregation of platelets, and hence are useful as a medicine.
