EC 3.1.6.1, also known as sulfatase, is an enzyme that catalyzes the hydrolysis of sulfate esters, removing sulfate groups from various substrates. It belongs to the EC 3 class of enzymes, which are hydrolases acting on ester bonds. Sulfates are widely found in nature, including carbohydrates, lipids, and proteins, and their removal is crucial for various biological processes. Sulfate esters are involved in cell signaling, cell recognition, and extracellular matrix interactions. The sulfatase enzyme is essential for the proper functioning of these molecules. Sulfate esters are also found in xenobiotics, and their removal is necessary for detoxification processes.
Source:
Sulfatases are found in various organisms, including mammals, plants, and microorganisms. In mammals, they are mainly found in lysosomes, where they play a crucial role in the degradation of sulfated macromolecules. In plants, they are involved in the modification of cell wall components and signaling molecules. In microorganisms, they are involved in the degradation of sulfated xenobiotics.
Production Methods:
Sulfatases can be produced through recombinant DNA technology, where the gene encoding the enzyme is inserted into a suitable expression system, such as bacteria, yeast, or mammalian cells. The recombinant enzyme can then be purified from the host organism for various applications.
Source:
Sulfatases are found in various organisms, including mammals, plants, and microorganisms. In mammals, they are mainly found in lysosomes, where they play a crucial role in the degradation of sulfated macromolecules. In plants, they are involved in the modification of cell wall components and signaling molecules. In microorganisms, they are involved in the degradation of sulfated xenobiotics.
Production Methods:
Sulfatases can be produced through recombinant DNA technology, where the gene encoding the enzyme is inserted into a suitable expression system, such as bacteria, yeast, or mammalian cells. The recombinant enzyme can then be purified from the host organism for various applications.
9016-17-5
Post Buying Request-
-
Basic information
- Product Name: EC 3.1.6.1
- Synonyms: SULFATASE;SULFATASE TYPE H-1;SULFATASE TYPE H-2;SULFATASE TYPE IV;SULFATASE TYPE V;SULFATASE TYPE VI;SULFATASE TYPE VIII;PHENOLSULFATASE
- CAS NO:9016-17-5
- Molecular Formula: NULL
- Molecular Weight: 0
- EINECS: 232-772-1
- Product Categories: N/A
-
Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /lyophilized powder
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: 2-8°C
- Solubility: N/A
- CAS DataBase Reference: EC 3.1.6.1(CAS DataBase Reference)
- NIST Chemistry Reference: EC 3.1.6.1(9016-17-5)
- EPA Substance Registry System: EC 3.1.6.1(9016-17-5)
-
Safety Data
- Hazard Codes: Xn
- Statements: 42/43
- Safety Statements: 22-24/25-45-36/37/39-36/37-23
- RIDADR: UN3373 - class 6.2 Biological substance, Category B
- WGK Germany: 3
- RTECS:
- F: 10-21
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 9016-17-5(Hazardous Substances Data)
9016-17-5 Suppliers
Recommended suppliers
9016-17-5 Usage
Uses
Used in Carbohydrate Analysis:EC 3.1.6.1 is used as a de-sulfation agent for the analysis of sulfated carbohydrates. Sulfated carbohydrates are important components of glycosaminoglycans, which are involved in various biological processes, including cell signaling, cell adhesion, and tissue repair. The removal of sulfate groups is necessary for the structural and functional analysis of these molecules.
Used in Drug Development:
Sulfatases are used in the development of drugs targeting sulfated molecules. The removal of sulfate groups can modulate the activity of these molecules, leading to potential therapeutic effects. For example, the removal of sulfate groups from certain steroid hormones can alter their biological activity, leading to the development of new drugs for hormone-related disorders.
Used in Detoxification Processes:
EC 3.1.6.1 is used in the detoxification of sulfated xenobiotics. Sulfated xenobiotics are often more toxic and less easily excreted than their non-sulfated counterparts. The removal of sulfate groups by sulfatases can facilitate their detoxification and elimination from the body.
Used in Food Industry:
Sulfatases are used in the food industry for the modification of food components. For example, they can be used to remove sulfate groups from carbohydrates in dairy products, improving their taste and texture. They can also be used to modify the structure of carbohydrates in bakery products, enhancing their quality and shelf life.
Used in Cosmetics Industry:
Sulfatases are used in the cosmetics industry for the modification of sulfated molecules in skincare products. The removal of sulfate groups can improve the skin's hydration, elasticity, and overall health. They can also be used to modify the structure of sulfated molecules in hair care products, improving their conditioning and styling properties.
Biochem/physiol Actions
Sulfatase from Helix pomatia facilitates the synthesis of thiohydroximates. It causes the hydrolysis of β-naphthyl sulfate much faster than a-naphthyl sulfate and possesses regiospecificity in the hydrolysis of ortho and para substituted phenyl sulfates.Check Digit Verification of cas no
The CAS Registry Mumber 9016-17-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 9,0,1 and 6 respectively; the second part has 2 digits, 1 and 7 respectively.Calculate Digit Verification of CAS Registry Number 9016-17:
(6*9)+(5*0)+(4*1)+(3*6)+(2*1)+(1*7)=85
85 % 10 = 5
So 9016-17-5 is a valid CAS Registry Number.
9016-17-5Upstream product
9016-17-5Downstream Products
Post a RFQ
1
What can I do for you?
Get Best Price
Get Best Price for 9016-17-5
EC 3.1.6.1
