90176-80-0 Usage
Chemical Properties
clear colorless liquid
Uses
Starting material for Fevipiprant. 4-Fluoro-2-(trifluoromethyl)benzaldehyde is also a reagent in the preparation of numerous inhibitors against proteins such as CRTH2, DP2 Receptor and Hepatitis B Virus (HBV) Capsid.
General Description
4-Fluoro-2-(trifluoromethyl)benzaldehyde is an organic fluorinated building block. It participates in the synthesis of diphenylthioethers. It also participates in the preparation of 1-cyano derivative of nilutamide.
Check Digit Verification of cas no
The CAS Registry Mumber 90176-80-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,0,1,7 and 6 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 90176-80:
(7*9)+(6*0)+(5*1)+(4*7)+(3*6)+(2*8)+(1*0)=130
130 % 10 = 0
So 90176-80-0 is a valid CAS Registry Number.
InChI:InChI=1/C8H4F4O/c9-6-2-1-5(4-13)7(3-6)8(10,11)12/h1-4H
90176-80-0Relevant articles and documents
Flow Chemistry on Multigram Scale: Continuous Synthesis of Boronic Acids within 1 s
Hafner, Andreas,Meisenbach, Mark,Sedelmeier, Joerg
supporting information, p. 3630 - 3633 (2016/08/16)
The benefits and limitations of a simple continuous flow setup for handling and performing of organolithium chemistry on the multigram scale is described. The developed metalation platform embodies a valuable complement to existing methodologies, as it combines the benefits of Flash Chemistry (chemical synthesis on a time scale of 1 s) with remarkable throughput (g/min) while mitigating the risk of blockages.