902137-40-0Relevant academic research and scientific papers
Total synthesis of (-)-martinellic acid via radical addition-cyclization- elimination reaction
Shirai, Atsushi,Miyata, Okiko,Tohnai, Norimitsu,Miyata, Mikiji,Procter, David J.,Sucunza, David,Naito, Takeaki
, p. 4464 - 4475 (2008/09/21)
(Chemical Equation Presented) The asymmetric total synthesis of martinellic acid, the first pyrrolo[3,2-c]quinoline alkaloid found in nature, is described. Three key steps in our synthesis of (-)-martinellic acid are the Bu 3SnH-promoted radica
An improved synthesis of (-)-martinellic acid via radical addition-cyclization-elimination reaction of chiral oxime ether
Miyata, Okiko,Shirai, Atsushi,Yoshino, Shintaro,Takeda, Yoshifumi,Sugiura, Makiko,Naito, Takeaki
, p. 893 - 896 (2007/10/03)
A concise formal synthesis of (-)-martinellic acid has been accomplished by preparing optically active dipyrroloquinoline as a key synthetic intermediate, which was prepared via the radical addition-cyclization-elimination of oxime ether carrying an unsaturated ester followed by two chemoselective reductions of the carbonyl groups. Georg Thieme Verlag Stuttgart.
