902141-08-6Relevant academic research and scientific papers
METHOD OF CONJUGATING AMINOTHIOL CONTAINING MOLECULES TO VEHICLES
-
Page/Page column 68; 69-70, (2008/06/13)
The present invention relates to a novel chemical process that provides novel vehicle derivatives that are exceptional 1,2- or 1,3-aminothiol specific reagents for conjugation to unprotected targeted compounds (e.g., polypeptides, peptides, or organic compounds) having or modified to have a 1,2- or 1,3 aminothiol group. The invention further relates to the methods of using novel water-soluble polymer derivatives and conjugates thereof.
