902142-07-8

Upstream product

• 1072-86-2 (1R,2R)-trans-1,2-cyclohexanediol 
• 902142-06-7 (1R,2R)-1,2-bis[2-ethoxycarbonyl-1-oxaethyl]cyclohexane 

Downstream Products

• 902142-08-9 (1R,2R)-1,2-bis[5-ethoxycarbonyl-1,4-dioxapentyl]cyclohexane 
• 902142-09-0 (1R,2R)-1,2-bis[2-(2-hydroxyethoxy)ethoxy]cyclohexane 

Relevant academic research and scientific papers

MACROCYCLIC CHELATORS AND METHODS OF USE THEREOF

Macrocyclic chelators (I) for chelation of alpha-emitting radiometal ions, such as actinium-225 are provided. Also provided are radiometal complexes containing an alpha-emitting radiometal ion bound to the macrocyclic chelator via coordinate bonding, and radioimmunoconjugates containing the radiometal complexes covalently linked to a targeting ligand, such as an antibody or antigen binding fragment thereof. The radioimmunoconjugates can be produced by click chemistry reactions. Methods of using the radiocomplexes and radioimmunoconjugates for selectively targeting neoplastic cells for radiotherapy and for treating neoplastic diseases and disorders are also described.

Macrocyclic cyclo[n]malonates - Synthetic aspects and observation of columnar arrangements by X-ray crystallography

A variety of achiral and chiral macrocyclic oligomalonates were synthesised in a one-step procedure through condensation of malonyl dichloride with α,ω-diols. We have investigated the applicability of this method by varying the length and type of the spac