902153-54-2Relevant academic research and scientific papers
Sequential addition reaction of lithium acetylides and Grignard reagents to thioiminium salts from thiolactams leading to 2,2-disubstituted cyclic amines
Murai, Toshiaki,Toshio, Rie,Mutoh, Yuichiro
, p. 6312 - 6320 (2006)
The reaction of thioiminium salts derived from γ- and δ-thiolactams with lithium acetylides and Grignard reagents proceeded sequentially to give 2,2-disubstituted pyrrolidines and piperidines in moderate to high yields. In the initial step of the reaction
