90220-57-8

Upstream product

• 62343-68-4 3-(3,5-dimethylphenyl)propan-1-ol 
• 100217-83-2 diethyl (3,5-dimethylphenylmethyl)malonate 
• 27129-86-8 1-bromomethyl-3,5-dimethylbenzene 

Downstream Products

• 90220-59-0 Sodium; 3-(3,5-dimethyl-phenyl)-propane-1-sulfonate 
• 1093172-64-5 [2,2-dimethyl-5-(2-{4-[3-(3,5-dimethylphenyl)propoxy]-3-trifluoromethylphenyl}ethyl)-1,3-dioxan-5-yl]carbamic acid t-butyl ester 
• 90220-34-1 N-cyclohexyl-3-(3,5-dimethylphenyl)-1-propane-sulfonamide 
• 90220-41-0 3-(3,5-dimethylphenyl)-N-phenyl-1-propane-sulfonamide 
• 90220-23-8 3-(3,5-dimethylphenyl)-1-propanesulfonyl azide 
• 90220-70-5 3-(3,5-Dimethyl-phenyl)-propane-1-sulfonyl chloride 
• 90220-28-3 3-(3,5-dimethylphenyl)-1-propane-sulfonamide 

Relevant academic research and scientific papers

Anodic benzylic C(sp3)-H amination: Unified access to pyrrolidines and piperidines

An electrochemical aliphatic C-H amination strategy was developed to access the important heterocyclic motifs of pyrrolidines and piperidines within a uniform reaction protocol. The mechanism of this unprecedented C-H amination strategy involves anodic C-H activation to generate a benzylic cation, which is efficiently trapped by a nitrogen nucleophile. The applicability of the process is demonstrated for 40 examples comprising both 5- and 6-membered ring formations.

AMINE COMPOUND AND PHARMACEUTICAL USE THEREOF

Provided is a novel amine compound represented by the following formula (I) having a superior peripheral blood lymphocyte decreasing action and superior in the immunosuppressive action, rejection suppressive action and the like, which shows decreased side effects of, for example, bradycardia and the like, or a pharmaceutically acceptable acid addition salt thereof, or a hydrate thereof, or a solvate thereof. wherein each symbol is as defined in the specification.