90221-46-8 Usage
General Description
6-Bromo-3-methyl-1H-indazole is a chemical compound with the molecular formula C8H7BrN2. It belongs to the class of indazole derivatives and contains a bromine atom and a methyl group. This chemical compound is commonly used as a building block in organic synthesis for the preparation of various pharmaceuticals, agrochemicals, and fine chemicals. Its structure and properties make it a versatile intermediate in the production of biologically active molecules. 6-Bromo-3-methyl-1H-indazole has a wide range of applications in the pharmaceutical and chemical industries due to its unique molecular structure and reactivity.
Check Digit Verification of cas no
The CAS Registry Mumber 90221-46-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,0,2,2 and 1 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 90221-46:
(7*9)+(6*0)+(5*2)+(4*2)+(3*1)+(2*4)+(1*6)=98
98 % 10 = 8
So 90221-46-8 is a valid CAS Registry Number.
90221-46-8Relevant articles and documents
Preparation method of pazopanib intermediate
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Paragraph 0163-0165, (2021/03/24)
The invention provides a preparation method of a pazopanib key intermediate 2,3-dimethyl-N-(2-chloropyrimidin-4-yl)-N-methyl-2H-indazole-6-amine. The method comprises the following steps: by taking 6-halogenated-2,3-dimethyl-2H-indazole as a raw material, conducting reacting to obtain N,2,3-trimethyl-2H-indazole-6-amine; and further carrying out a reaction to obtain the 2,3-dimethyl-N-(2-chloropyrimidin-4-yl)-N-methyl-2H-indazole-6-amine. The method has the advantages of short synthesis route, accessible raw materials, low cost, mild reaction conditions, high safety and high yield, and is suitable for industrial mass production.
