90221-46-8 Usage
Uses
Used in Pharmaceutical Industry:
6-Bromo-3-methyl-1H-indazole is used as a building block for the synthesis of various pharmaceuticals, contributing to the development of biologically active molecules with potential therapeutic applications.
Used in Agrochemical Industry:
6-Bromo-3-methyl-1H-indazole is utilized as a key intermediate in the production of agrochemicals, enabling the creation of effective compounds for crop protection and pest control.
Used in Fine Chemicals Industry:
6-Bromo-3-methyl-1H-indazole serves as a crucial component in the synthesis of fine chemicals, which are high-purity specialty chemicals used in various applications, including fragrances, dyes, and advanced materials.
Check Digit Verification of cas no
The CAS Registry Mumber 90221-46-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,0,2,2 and 1 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 90221-46:
(7*9)+(6*0)+(5*2)+(4*2)+(3*1)+(2*4)+(1*6)=98
98 % 10 = 8
So 90221-46-8 is a valid CAS Registry Number.
90221-46-8Relevant academic research and scientific papers
Preparation method of pazopanib intermediate
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Paragraph 0163-0165, (2021/03/24)
The invention provides a preparation method of a pazopanib key intermediate 2,3-dimethyl-N-(2-chloropyrimidin-4-yl)-N-methyl-2H-indazole-6-amine. The method comprises the following steps: by taking 6-halogenated-2,3-dimethyl-2H-indazole as a raw material, conducting reacting to obtain N,2,3-trimethyl-2H-indazole-6-amine; and further carrying out a reaction to obtain the 2,3-dimethyl-N-(2-chloropyrimidin-4-yl)-N-methyl-2H-indazole-6-amine. The method has the advantages of short synthesis route, accessible raw materials, low cost, mild reaction conditions, high safety and high yield, and is suitable for industrial mass production.
