90243-53-1Relevant academic research and scientific papers
Investigation of reaction mechanism of amino acids and phosphorus trichloride by 31P NMR and ESI-MS/MS
Cao, Yanchun,Cao, Shuxia,Xie, Yali,Zong, Xiangkun,Zhao, Yufen
, p. 1173 - 1179 (2011)
The reaction of amino acids and phosphorus trichloride in THF was studied by 31P NMR tracing and ESI-MS/MS. A series of hydridophoranes and cyclic dipeptides were obtained. The reaction presented interesting diversity and the reaction mechanism was proposed. The mechanism suggests that phosphorus plays an important role in the synthesis of amino acid hydridophorane and cyclic dipeptides. The results also show that 31P NMR and ESI-MS/MS are useful tools for the investigation of reaction mechanism. Copyright
