90244-12-5

Upstream product

• 7699-00-5 (R)-Ethyl lactate 
• 68057-04-5 (1R,5S)-3-phenyl-6-(1-diphenylmethoxycarbonyl-2-methylprop-1-enyl)-7-oxo-4-oxa-2,6-diazabicyclo[3.2.0]hept-2-ene 

Downstream Products

• 130793-08-7 Sodium; (R)-2-[(2R,3R)-1-(1-benzhydryloxycarbonyl-2-methyl-propenyl)-3-benzoylamino-4-oxo-azetidin-2-yloxy]-propionate 
• 130792-99-3 (S)-2-((2R,3R)-1-Benzhydryloxyoxalyl-3-benzoylamino-4-oxo-azetidin-2-yloxy)-propionic acid ethyl ester 
• 130675-30-8 (5S,7R,8R)-8-Benzoylamino-5-methyl-4,9-dioxo-6-oxa-1-aza-bicyclo[5.2.0]non-2-ene-2-carboxylic acid benzhydryl ester 
• 90211-54-4 (3R,4R)-4-{(1R)-1-carboxyethoxy}-3-benzamido-1-(1-diphenylmethoxycarbonyl-1-triphenylphosphoranylidenemethyl)azetidin-2-one 
• 90244-28-3 (3R,4R)-4-{(1S)-1-carboxyethoxy}-3-benzamido-1-(1-diphenylmethoxycarbonyl-1-triphenylphosphoranylidenemethyl)azetidin-2-one 
• 90244-30-7 (3R,4R)-4-{(1S)-3-chloro-2-oxo-1-methylpropoxy}-3-benzamido-1-(1-diphenylmethoxycarbonyl-1-triphenylphosphoranylidenemethyl)azetidin-2-one 
• 90211-56-6 (3R,4R)-4-{(1R)-3-diazo-2-oxo-1-methylpropoxy}-3-benzamido-1-(1-diphenylmethoxycarbonyl-1-triphenylphosphoranylidenemethyl)azetidin-2-one 
• 90244-29-4 (3R,4R)-4-{(1S)-3-diazo-2-oxo-1-methylpropoxy}-3-benzamido-1-(1-diphenylmethoxycarbonyl-1-triphenylphosphoranylidenemethyl)azetidin-2-one 
• 90211-53-3 (3R,4R)-4-{(1R)-1-ethoxycarbonylethoxy}-3-benzamido-1-(1-diphenylmethoxycarbonyl-1-triphenylphosphoranylidenemethyl)azetidin-2-one 
• 90244-27-2 (3R,4R)-4-{(1S)-1-ethoxycarbonylethoxy}-3-benzamido-1-(1-diphenylmethoxycarbonyl-1-triphenylphosphoranylidenemethyl)azetidin-2-one 
• 130675-28-4 [(2R,3R)-2-((R)-3-Acetoxy-1-methyl-2-oxo-propoxy)-3-benzoylamino-4-oxo-azetidin-1-yl]-(triphenyl-λ⁵-phosphanylidene)-acetic acid benzhydryl ester 
• 130675-28-4 [(2R,3R)-2-((S)-3-Acetoxy-1-methyl-2-oxo-propoxy)-3-benzoylamino-4-oxo-azetidin-1-yl]-(triphenyl-λ⁵-phosphanylidene)-acetic acid benzhydryl ester 
• 130675-27-3 [(2R,3R)-3-Benzoylamino-2-((R)-2-ethoxycarbonyloxy-1-methyl-2-oxo-ethoxy)-4-oxo-azetidin-1-yl]-(triphenyl-λ⁵-phosphanylidene)-acetic acid benzhydryl ester 
• 130675-27-3 [(2R,3R)-3-Benzoylamino-2-((S)-2-ethoxycarbonyloxy-1-methyl-2-oxo-ethoxy)-4-oxo-azetidin-1-yl]-(triphenyl-λ⁵-phosphanylidene)-acetic acid benzhydryl ester 

Relevant academic research and scientific papers

NOVEL 2-METHYL-1-OXACEPHALOSPORINS 1. SYNTHESIS OF 2-METHYL-3-NOR-1-OXACEPHEM NUCLEUS

The 2α- and 2β-methyl-1-oxacephems were synthesized stereoselectively starting from (3R,4S)-oxazolinoazetidinone by reaction with chiral alcohols followed by intramolecular carbene insertion of α-diazo-β-keto intermediates.

1-Oxa-1-dethia-cephalosporin derivatives

This invention relates to 1-oxa-1-dethia-cephalosporins which are useful as anti-biotics.