90252-70-3Relevant academic research and scientific papers
One-pot multi-component approach to the synthesis of 1,4-benzothiazines in aqueous media
Sheibani, Hassan,Islami, Mohammad Reza,Hassanpour, Avid,Saidi, Kazem
, p. 13 - 20 (2008/12/21)
A new and rapid synthetic strategy for the oxidative cyclocondensation of 2-aminobenzenethiol and 1,3-dicarbonyls has been developed in order to obtain 2,3-disubstituted 1,4-benzothiazines at ambient temperature and in aqueous media. A mechanism is presen
Reactions of 1,2-diaza-1,3-dienes with thiol derivatives: a versatile construction of nitrogen/sulfur containing heterocycles
Attanasi, Orazio A.,Filippone, Paolino,Lillini, Samuele,Mantellini, Fabio,Nicolini, Simona,de los Santos, Jesús M.,Ignacio, Roberto,Aparicio, Domitila,Palacios, Francisco
, p. 9264 - 9274 (2008/12/21)
The synthesis of substituted 2,3-dihydro-1,4-thiazines, fused cycloalkyl-1,4-thiazines, 1,4-benzothiazines and fused cycloalkyl-1,4-benzothiazines by 1,4-addition of 1,2-aminothiols to 1,2-diaza-1,3-dienes bearing carboxylate, carboxamide, or phosphorylated groups and subsequent internal heterocyclization is described. The reaction of carboxylated 1,2-diaza-1,3-butadienes with 2-(butylamino)ethanethiol affords 1,4-thiazinan-3-ones. The solid-phase reaction of polymer-bound 1,2-diaza-1,3-butadienes with 1,2-aminothiols produces 2,3-dihydro-1,4-thiazines and 1,4-benzothiazines.
