902524-15-6Relevant articles and documents
Synthesis and anti-inflammatory activity of fluorinated isocoumarins and 3,4-dihydroisocoumarins
Qadeer, Ghulam,Rama, Nasim Hasan,Gardu?o-Ramírez
, p. 641 - 646 (2008/01/06)
The synthesis of several fluorinated isocoumarins and 3,4-dihydroisocoumarins are described. The structures of the synthesized compounds were confirmed by spectral and elemental analysis. All synthesized compounds were evaluated for their anti-inflammatory and antioxidant activity. These compounds were found to present antioxidant and anti-inflammatory activities. A few of them were found to be significantly active in vivo against ear edema in mice produced by 12-O-tetradecanoylphorbol-13-acetate (TPA) and also good radical scavengers.