Adenylosuccinate lyase, also known as adenylosuccinate lyase (ADSL), is an enzyme that plays a crucial role in the de novo purine nucleotide synthesis pathway. It catalyzes the conversion of adenylosuccinate to AMP (adenosine monophosphate) and fumarate, which is an essential step in the production of purine nucleotides, the building blocks of DNA and RNA. This enzyme is found in various organisms, including humans, and its deficiency can lead to a rare genetic disorder called adenylosuccinate lyase deficiency, characterized by developmental delays, seizures, and intellectual disability. Adenylosuccinate lyase is also involved in the regulation of purine metabolism and has potential therapeutic implications in the treatment of certain diseases associated with purine metabolism disorders.
The CAS Registry Mumber 9027-81-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 9,0,2 and 7 respectively; the second part has 2 digits, 8 and 1 respectively. Calculate Digit Verification of CAS Registry Number 9027-81: (6*9)+(5*0)+(4*2)+(3*7)+(2*8)+(1*1)=100 100 % 10 = 0 So 9027-81-0 is a valid CAS Registry Number.