902773-17-5

Basic information

• Product Name: N-phenyl-2-((2-(trimethylsilyl)ethoxy)methyl)-2H-indazole-3-carboxamide
• Synonyms: N-phenyl-2-((2-(trimethylsilyl)ethoxy)methyl)-2H-indazole-3-carboxamide
• CAS NO: 902773-17-5
• Molecular Weight: 367.523
• Mol File: 902773-17-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-phenyl-2-((2-(trimethylsilyl)ethoxy)methyl)-2H-indazole-3-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-phenyl-2-((2-(trimethylsilyl)ethoxy)methyl)-2H-indazole-3-carboxamide(902773-17-5)
• EPA Substance Registry System: N-phenyl-2-((2-(trimethylsilyl)ethoxy)methyl)-2H-indazole-3-carboxamide(902773-17-5)

Safety Data

• Hazardous Substances Data: 902773-17-5(Hazardous Substances Data)

Upstream product

• 271-44-3 benzimidazole 
• 902773-08-4 2-((2-(trimethylsilyl)ethoxy)methyl)-2H-indazole 
• 103-71-9 phenyl isocyanate 

Relevant articles and documents

Regioselective protection at N-2 and derivatization at C-3 of indazoles

Indazoles are regioselectively protected at N-2 by a 2-(trimethylsilyl) ethoxymethyl (SEM) group using novel conditions. The SEM group can efficiently direct regioselective C-3 lithiation, and the resulting nucleophile can react with a wide range of electrophiles to generate novel indazole derivatives. The SEM group can be removed by treatment with TBAF in THF or aqueous HCl in EtOH.