9028-12-0

Basic information

• Product Name: EC 1.1.1.2
• Synonyms: EC 1.1.1.2;KETOREDUCTASE LB;KETOREDUCTASE T;KETOREDUCTASE CDX003;ALCOHOL DEHYDROGENASE CDX003;ALCOHOL DEHYDROGENASE LB;ALCOHOL DEHYDROGENASE, NADP+ DEPENDENT;ALCOHOL DEHYDROGENASE T
• CAS NO: 9028-12-0
• Molecular Weight: 0
• EINECS: 232-823-8
• Product Categories: Oxidoreductases;Specialty Enzymes
• Mol File: 9028-12-0.mol
• Article Data: 0

Chemical Properties

• Appearance: white/powder
• Storage Temp.: −20°C
• CAS DataBase Reference: EC 1.1.1.2(CAS DataBase Reference)
• NIST Chemistry Reference: EC 1.1.1.2(9028-12-0)
• EPA Substance Registry System: EC 1.1.1.2(9028-12-0)

Safety Data

• Hazard Codes: Xn
• Statements: 42/43
• Safety Statements: 22-36/37-45
• WGK Germany: 3
• F: 10-21
• Hazardous Substances Data: 9028-12-0(Hazardous Substances Data)

Usage

Uses

Component of NADH recycling systems. Substrate specificity limited to low molecular weight alcohols.

General Description

Alcohol:NAD+ oxidoreductase.Alcohol dehydrogenase (ADH) from yeast is a metalloenzyme containing four zinc atoms per molecule. NAD+ is its coenzyme.

Biochem/physiol Actions

Alcohol dehydrogenase catalyzes the oxidative conversion of alcohol into aldehyde. It has a homodimeric structure with a co-enzyme binding domain at the C-terminal and an N-terminal catalytic domain. The active site is located at the interdomain cleft. Binding of NAD+ in the active site causes conformational changes which create the binding site for the alcohol substrate.