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EC 1.1.1.2, also known as Alcohol dehydrogenase (ADH), is a metalloenzyme that plays a crucial role in the metabolism of alcohols. It is found in various organisms, including yeast, and contains four zinc atoms per molecule. Its coenzyme is NAD+, which is essential for its catalytic activity.
Source:
Alcohol dehydrogenase (ADH) is typically found in yeast and other organisms.
Production Methods:
The production of EC 1.1.1.2 involves the synthesis of the enzyme through the expression of the corresponding gene in suitable host organisms, such as yeast or bacteria.

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  • 9028-12-0 Structure
  • Basic information

    1. Product Name: EC 1.1.1.2
    2. Synonyms: EC 1.1.1.2;KETOREDUCTASE LB;KETOREDUCTASE T;KETOREDUCTASE CDX003;ALCOHOL DEHYDROGENASE CDX003;ALCOHOL DEHYDROGENASE LB;ALCOHOL DEHYDROGENASE, NADP+ DEPENDENT;ALCOHOL DEHYDROGENASE T
    3. CAS NO:9028-12-0
    4. Molecular Formula:
    5. Molecular Weight: 0
    6. EINECS: 232-823-8
    7. Product Categories: Oxidoreductases;Specialty Enzymes
    8. Mol File: 9028-12-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: white/powder
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: −20°C
    8. Solubility: N/A
    9. CAS DataBase Reference: EC 1.1.1.2(CAS DataBase Reference)
    10. NIST Chemistry Reference: EC 1.1.1.2(9028-12-0)
    11. EPA Substance Registry System: EC 1.1.1.2(9028-12-0)
  • Safety Data

    1. Hazard Codes: Xn
    2. Statements: 42/43
    3. Safety Statements: 22-36/37-45
    4. WGK Germany: 3
    5. RTECS:
    6. F: 10-21
    7. HazardClass: N/A
    8. PackingGroup: N/A
    9. Hazardous Substances Data: 9028-12-0(Hazardous Substances Data)

9028-12-0 Usage

Uses

Used in Biochemical Research:
EC 1.1.1.2 is used as a research tool for studying the metabolism of alcohols and the role of NAD+ in redox reactions. It helps researchers understand the mechanisms of alcohol oxidation and the regulation of NAD+/NADH ratios in cells.
Used in NADH Recycling Systems:
EC 1.1.1.2 is used as a component of NADH recycling systems to maintain a high NAD+/NADH ratio during biotransformation processes. This is particularly important in industrial applications where the regeneration of NAD+ is required for efficient and sustainable production of desired compounds.
Used in the Production of Chiral Compounds:
Due to its substrate specificity for low molecular weight alcohols, EC 1.1.1.2 is used in the production of chiral compounds with high enantioselectivity. This is particularly relevant in the pharmaceutical industry, where enantiomerically pure compounds are often required for drug development.
Used in the Food and Beverage Industry:
EC 1.1.1.2 is used in the fermentation process to produce alcohol, which is a key component in various food and beverage products, such as bread, beer, and wine. The enzyme plays a crucial role in the conversion of sugars into alcohol, contributing to the final product's taste and quality.
Used in the Production of Biofuels:
EC 1.1.1.2 is employed in the production of biofuels, such as ethanol, through the fermentation of biomass. The enzyme catalyzes the conversion of sugars into alcohol, which can be used as a renewable and environmentally friendly energy source.

Biochem/physiol Actions

Alcohol dehydrogenase catalyzes the oxidative conversion of alcohol into aldehyde. It has a homodimeric structure with a co-enzyme binding domain at the C-terminal and an N-terminal catalytic domain. The active site is located at the interdomain cleft. Binding of NAD+ in the active site causes conformational changes which create the binding site for the alcohol substrate.

Check Digit Verification of cas no

The CAS Registry Mumber 9028-12-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 9,0,2 and 8 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 9028-12:
(6*9)+(5*0)+(4*2)+(3*8)+(2*1)+(1*2)=90
90 % 10 = 0
So 9028-12-0 is a valid CAS Registry Number.

9028-12-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name Alcohol Dehydrogenase, recombinant from E. coli

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:9028-12-0 SDS

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