EC 1.1.1.22 is an enzyme commission number that refers to the chemical name "Glucose-6-phosphate dehydrogenase" (G6PD). This enzyme plays a crucial role in the pentose phosphate pathway, specifically in the first step of this metabolic pathway. G6PD catalyzes the oxidation of glucose-6-phosphate to 6-phosphogluconolactone, while simultaneously converting NADP+ to NADPH. NADPH is an essential reducing agent in various cellular processes, including the synthesis of fatty acids and the maintenance of cellular antioxidants. G6PD is also important for the regeneration of reduced glutathione, which protects cells from oxidative stress. The enzyme is widely distributed in various tissues, with high concentrations found in the liver, kidney, and red blood cells. Deficiency in G6PD can lead to hemolytic anemia and other health issues, making it a significant enzyme in human metabolism and health.
Synonyms: uridine-5'-diphosphoglucose*dehydrogenase type ii;Dehydrogenase, uridine diphosphoglucose;URIDINE-5'-DIPHOSPHOGLUCOSE*DEHYDROGENAS E TYPE VI F;uridine-5'-diphosphoglucose dehydrogenase from bovine liver;UDP-GLUCOSE DEHYDROGENASE, E.COLI, RECOMBINANT;Uridine-5-diphosphoglucose Dehydrogenase;Uridine-5′-diphosphoglucose Dehydrogenase from Streptococcus pyogenes;EC 1.1.1.22
The CAS Registry Mumber 9028-26-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 9,0,2 and 8 respectively; the second part has 2 digits, 2 and 6 respectively. Calculate Digit Verification of CAS Registry Number 9028-26: (6*9)+(5*0)+(4*2)+(3*8)+(2*2)+(1*6)=96 96 % 10 = 6 So 9028-26-6 is a valid CAS Registry Number.