Carnitine acetyltransferase, also known as CRAT, is a mitochondrial enzyme that plays a crucial role in fuel utilization and fatty acid metabolism. It is found in the mitochondrial matrix and peroxisome, where it catalyzes the reversible conversion of acetyl-CoA and carnitine into acetylcarnitine and CoA. This conversion is essential for peroxisomal β-oxidation, as it imports the acetyl group for mitochondrial oxidation.
9029-90-7
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Basic information
- Product Name: CARNITINE ACETYLTRANSFERASE
- Synonyms: CARNITINE ACETYLTRANSFERASE;EC 2.3.1.7;ACETYL-CO-A: CARNITINE-O-ACETYLTRANSFERASE;carnitine acetyltransferase from pigeon breast M.,~100 U/mg;Carnitine Acetyltransferase pigeon breast muscle;Acetyltransferase, carnitine;CARNITINE ACETYLTRANSFERASEFROM PIGEON B REAST MUSC;carnitine acetyltransferase from pigeon breast muscle
- CAS NO:9029-90-7
- Molecular Formula:
- Molecular Weight: 0
- EINECS: 232-854-7
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /ammonium sulfate suspension
- Density: 1.00 g/mL at 20 °C
- Refractive Index: N/A
- Storage Temp.: 2-8°C
- Solubility: N/A
- CAS DataBase Reference: CARNITINE ACETYLTRANSFERASE(CAS DataBase Reference)
- NIST Chemistry Reference: CARNITINE ACETYLTRANSFERASE(9029-90-7)
- EPA Substance Registry System: CARNITINE ACETYLTRANSFERASE(9029-90-7)
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Safety Data
- Hazard Codes: Xi
- Statements: 36/37/38
- Safety Statements: 26-36
- WGK Germany: 3
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 9029-90-7(Hazardous Substances Data)
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9029-90-7 Usage
Uses
Used in Biochemical Research:Carnitine acetyltransferase is used as a research tool in biochemical studies for understanding the role of fatty acid metabolism in various cellular processes. It helps researchers investigate the mechanisms of energy production and the regulation of lipid metabolism.
Used in Pharmaceutical Development:
Carnitine acetyltransferase is used in the development of pharmaceuticals targeting metabolic disorders and diseases related to lipid metabolism. By modulating the activity of this enzyme, it may be possible to develop treatments for conditions such as obesity, diabetes, and cardiovascular diseases.
Used in Nutritional Supplements:
Carnitine acetyltransferase may be used in the formulation of nutritional supplements designed to support healthy lipid metabolism and energy production. These supplements could potentially help individuals with specific metabolic needs or those looking to optimize their physical performance.
Used in Diagnostic Applications:
Carnitine acetyltransferase can be employed in diagnostic tests to assess the functionality of fatty acid metabolism in individuals. Abnormal levels or activity of this enzyme may indicate underlying metabolic disorders or diseases, allowing for early detection and intervention.
Used in Agricultural Industry:
In the agricultural industry, carnitine acetyltransferase may be used to improve the efficiency of lipid metabolism in livestock, leading to better feed conversion ratios and overall health. This could contribute to sustainable and efficient animal production.
Used in Cosmetics Industry:
Carnitine acetyltransferase could be incorporated into cosmetic products, particularly those targeting skin health and rejuvenation. By promoting healthy lipid metabolism, it may help improve skin elasticity, reduce the appearance of fine lines and wrinkles, and maintain overall skin vitality.
Biochem/physiol Actions
Carnitine acetyltransferase maintains the cellular and mitochondrial levels of acetyl-CoA, a key cofactor required for oxidative metabolism, by catalyzing an equilibrium between acetyl-CoA and acetyl-L-carnitine, a storage form of activated acetate. Carnitine acetyltransferase also maintains the pool of acetyl-CoA required for neuronal and nonneuronal acetylcholine production.Check Digit Verification of cas no
The CAS Registry Mumber 9029-90-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 9,0,2 and 9 respectively; the second part has 2 digits, 9 and 0 respectively.Calculate Digit Verification of CAS Registry Number 9029-90:
(6*9)+(5*0)+(4*2)+(3*9)+(2*9)+(1*0)=107
107 % 10 = 7
So 9029-90-7 is a valid CAS Registry Number.
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CARNITINE ACETYLTRANSFERASE
