90291-46-6

Basic information

• Product Name: N-(1-NAPHTHALENESULFONYL)-L-PHENYLALANINE
• Synonyms: N-(1-NAPHTHALENESULFONYL)-L-PHENYLALANINE;Naphthalenesulfonylphenylalanine;N-(1-NAPHTHALENESULFONYL)-L-PHENYLALANINE 98+%;N-(1-Naphthalenesulfonyl)-L-phenylalanine
• CAS NO: 90291-46-6
• Molecular Formula: C₁₉H₁₇NO₄S
• Molecular Weight: 355.41
• Mol File: 90291-46-6.mol
• Article Data: 1

Chemical Properties

• Melting Point: 141 °C
• Appearance: /
• Refractive Index: -33 ° (C=3, Acetone)
• Solubility: almost transparency in Acetone
• CAS DataBase Reference: N-(1-NAPHTHALENESULFONYL)-L-PHENYLALANINE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(1-NAPHTHALENESULFONYL)-L-PHENYLALANINE(90291-46-6)
• EPA Substance Registry System: N-(1-NAPHTHALENESULFONYL)-L-PHENYLALANINE(90291-46-6)

Safety Data

• Hazardous Substances Data: 90291-46-6(Hazardous Substances Data)

Usage

Description

N-(1-NAPHTHALENESULFONYL)-L-PHENYLALANINE is a chemical compound that serves as a protecting group for the amino acid phenylalanine in the field of organic synthesis. It features a naphthalenesulfonyl group attached to phenylalanine, which effectively masks the amino acid's functionality during chemical reactions. The naphthalenesulfonyl group can be easily removed under mild conditions, allowing for the regeneration of the free amino acid. N-(1-NAPHTHALENESULFONYL)-L-PHENYLALANINE is widely used in peptide synthesis and other organic chemistry applications where selective protection and deprotection of amino acids are necessary.

Uses

Used in Organic Synthesis:
N-(1-NAPHTHALENESULFONYL)-L-PHENYLALANINE is used as a protecting group for [the amino acid phenylalanine] for [masking its functionality during chemical reactions and allowing for selective protection and deprotection].
Used in Peptide Synthesis:
N-(1-NAPHTHALENESULFONYL)-L-PHENYLALANINE is used as a protecting agent for [phenylalanine residues in peptides] for [enabling the controlled synthesis of peptide sequences by preventing unwanted side reactions].
Used in Other Organic Chemistry Applications:
N-(1-NAPHTHALENESULFONYL)-L-PHENYLALANINE is used as a selective protecting group for [amino acids in various organic chemistry reactions] for [facilitating the synthesis of complex organic molecules by controlling the reactivity of specific functional groups].

Upstream product

• 150-30-1 Phenylalanine 
• 85-46-1 1-Naphthalenesulfonyl chloride 

Downstream Products

• 90291-84-2 4-[2-(Naphthalene-1-sulfonylamino)-3-phenyl-propionylamino]-thiobenzimidic acid methyl ester; hydriodide 
• 90291-83-1 3-[2-(Naphthalene-1-sulfonylamino)-3-phenyl-propionylamino]-thiobenzimidic acid methyl ester; hydriodide 
• 90291-73-9 2-(Naphthalene-1-sulfonylamino)-3-phenyl-N-(4-thiocarbamoyl-phenyl)-propionamide 
• 90291-72-8 2-(Naphthalene-1-sulfonylamino)-3-phenyl-N-(3-thiocarbamoyl-phenyl)-propionamide 
• 90291-60-4 N-(3-Cyano-phenyl)-2-(naphthalene-1-sulfonylamino)-3-phenyl-propionamide 
• 90291-96-6 (S)-N-(4-Carbamimidoyl-phenyl)-2-(naphthalene-1-sulfonylamino)-3-phenyl-propionamide; hydriodide 
• 90291-95-5 (S)-N-(3-Carbamimidoyl-phenyl)-2-(naphthalene-1-sulfonylamino)-3-phenyl-propionamide; hydriodide 
• 90291-61-5 N_α-(1-Naphthylsulfonyl)phenylalanin-4-cyananilid 
• 90291-51-3 2-(Naphthalene-1-sulfonylamino)-3-phenyl-propionyl chloride 

Relevant articles and documents

Synthesis of α-(arylsulphonylamino)-ω-phenylalkylcarboxylic acid 3- and -4-amidinoanilides

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