90293-07-5Relevant academic research and scientific papers
Stereochemistry of Aryl Methyl Phosphorochloridothionates as Chiral Two-step Phosphorylating Reagents
Shao-Yong, Wu,Eto, Morifusa
, p. 3071 - 3080 (2007/10/02)
Seven aryl methyl phosphorochloridothionates were prepared and examined for reactivity as two-step phosphorylating reagents to synthesize oxazaphospholidine sulfide.The 2,6-dichloro-4-methylphenyl and p-nitrophenyl derivatives (CMPC and MNPC) were selecte
Synthesis of Optically Active Cyclic Phosphorothionates and Phosphoramidothionates with Insecticidal Activity by Using a Chiral Phosphorylating Agent
Hirashima, Akinori,Eto, Morifusa
, p. 2831 - 2840 (2007/10/02)
Chiral methyl p-nitrophenyl phosphorochloridothionate (MNPC) was utilized as a phosphorylating agent in the synthesis of optically active cyclic phosphorus esters including the enantiomers of 2-methoxy-4H-1,3,2-benzodioxaphosphorin 2-sulfide (salithion) and four diastereomers of 4-isobutyl-2-methoxy-1,3,2-oxazaphospholidine 2-sulfide (BMOS).Their insecticidal activity decreased in the following order; (S) > (R) in salithion and (S)P(S)C > (S)P(R)C > (R)P(R)C > (R)P(S)C in BMOS.
