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2-TERT-BUTOXYCARBONYLAMINO-OXAZOLE-5-CARBOXYLIC ACID is a monocyclic OGA (O-GlcNAcase) inhibitor compound that plays a crucial role in the regulation of cellular O-GlcNAcylation levels. 2-TERT-BUTOXYCARBONYLAMINO-OXAZOLE-5-CARBOXYLIC ACID is characterized by its unique structure, which includes a tert-butoxycarbonyl group, an amino group, an oxazole ring, and a carboxylic acid group. These structural features contribute to its ability to inhibit OGA activity, thereby modulating cellular processes and potentially offering therapeutic benefits in various applications.

903094-60-0

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903094-60-0 Usage

Uses

Used in Pharmaceutical Industry:
2-TERT-BUTOXYCARBONYLAMINO-OXAZOLE-5-CARBOXYLIC ACID is used as a monocyclic OGA inhibitor for the development of therapeutic agents targeting various diseases and conditions. 2-TERT-BUTOXYCARBONYLAMINO-OXAZOLE-5-CARBOXYLIC ACID's ability to modulate O-GlcNAcylation levels can have significant implications for the treatment of metabolic disorders, neurodegenerative diseases, and cancer, among others. By inhibiting OGA activity, 2-TERT-BUTOXYCARBONYLAMINO-OXAZOLE-5-CARBOXYLIC ACID can help restore the balance of O-GlcNAcylation, which is often disrupted in these pathological conditions.
Used in Research Applications:
In addition to its potential therapeutic applications, 2-TERT-BUTOXYCARBONYLAMINO-OXAZOLE-5-CARBOXYLIC ACID is also used as a research tool to study the role of O-GlcNAcylation in cellular processes and disease mechanisms. Researchers can utilize 2-TERT-BUTOXYCARBONYLAMINO-OXAZOLE-5-CARBOXYLIC ACID to investigate the effects of OGA inhibition on cellular signaling pathways, gene expression, and protein function, providing valuable insights into the underlying mechanisms of various diseases and conditions.
Used in Drug Development:
2-TERT-BUTOXYCARBONYLAMINO-OXAZOLE-5-CARBOXYLIC ACID serves as a key starting point for the development of novel OGA inhibitors with improved potency, selectivity, and pharmacokinetic properties. By optimizing the structure and functional groups of 2-TERT-BUTOXYCARBONYLAMINO-OXAZOLE-5-CARBOXYLIC ACID, chemists can design and synthesize new OGA inhibitors with enhanced therapeutic potential and reduced side effects. These next-generation inhibitors can then be further evaluated in preclinical and clinical studies to assess their safety, efficacy, and suitability for various medical applications.

Check Digit Verification of cas no

The CAS Registry Mumber 903094-60-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,0,3,0,9 and 4 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 903094-60:
(8*9)+(7*0)+(6*3)+(5*0)+(4*9)+(3*4)+(2*6)+(1*0)=150
150 % 10 = 0
So 903094-60-0 is a valid CAS Registry Number.

903094-60-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-((tert-Butoxycarbonyl)amino)oxazole-5-carboxylic acid

1.2 Other means of identification

Product number -
Other names 2-[(2-methylpropan-2-yl)oxycarbonylamino]-1,3-oxazole-5-carboxylic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:903094-60-0 SDS

903094-60-0Downstream Products

903094-60-0Relevant academic research and scientific papers

GLYCOSIDASE INHIBITORS

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Page/Page column 78; 79, (2014/10/15)

Compounds of formula (I) wherein X1, X2, W, R1 to R5, L and m have the meaning according to the claims, are glucosidase inhibitors, and can be employed, inter alia, for the treatment of Alzheimer's disease.

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