9031-54-3

Basic information

• Product Name: SPHINGOMYELINASE
• Synonyms: SPHINGOMYELINASE;SPHINGOMYELINASE, STAPHYLOCOCCUS AUREUS;SPHINGOMYELIN CHOLINE PHOSPHOHYDROLASE;SPHINGOMYELIN PHOSPHODIESTERASE;EC 3.1.4.12;sphingomyelinase from human placenta;Sphingomyelinase C;SPHINGOMYELINASE FROM STAPHYLOCOCCUS*AUR EUS
• CAS NO: 9031-54-3
• Molecular Weight: 0
• EINECS: 232-869-9
• Mol File: 9031-54-3.mol
• Article Data: 0

Chemical Properties

• Appearance: /lyophilized powder
• Storage Temp.: 2-8°C
• CAS DataBase Reference: SPHINGOMYELINASE(CAS DataBase Reference)
• NIST Chemistry Reference: SPHINGOMYELINASE(9031-54-3)
• EPA Substance Registry System: SPHINGOMYELINASE(9031-54-3)

Safety Data

• Hazard Codes: B
• Safety Statements: 23-24/25
• WGK Germany: 3
• Hazardous Substances Data: 9031-54-3(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 9031-54-3 differently. You can refer to the following data:
1. sphingomyelinase is a fluid that can enhance the skin’s moistureretention properties.
2. Sphingomyelinase from Bacillus cereus has been used:in the measurement of membrane capacitance in brain slicesfor testing and confirming its silkworm-killing activityin enzyme activity assay and for elucidating its effect on hydrolysis of sphingomyelin in complex lipid mixtures
3. Sphingomyelinase from Staphylococcus aureus has been used to:induce neurotoxicity in rat cortical cultures to study the protective effects of minocyclinedetermine the concentration of sphingomyelin from serum samplesenhance sphingomyelinase activity to study PARK9-mediated exosome biogenesis

General Description

Sphingomyelinase from Bacillus cereus (Bc-Smase) is a Mg2+-containing metalloenzyme. Bacillus cereus sphingomyelinase induces hemolysis of sheep erythrocytes.

Biochem/physiol Actions

Initiates the formation of sphingomyelin-based second messengers. Activates MAPK (mitogen-activated protein kinase) and SAPKs (stress-activated protein kinases); generates ceramide from sphingomyelin.