5-Formiminotetrahydrofolate: L-glutamate N-formiminotransferase is an enzyme that plays a crucial role in the metabolism of certain amino acids, particularly histidine. This enzyme catalyzes the transfer of a formimino group from 5-formiminotetrahydrofolate to L-glutamate, resulting in the formation of 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR) and tetrahydrofolate. AICAR is an intermediate in the de novo purine synthesis pathway, which is essential for the production of nucleotides and nucleic acids. The enzyme's activity is regulated by various factors, including the availability of its substrates and the presence of certain cofactors. Understanding the function and regulation of this enzyme is important for studying the metabolic pathways involved in amino acid metabolism and purine synthesis, as well as for developing potential therapeutic strategies targeting these pathways in various diseases.
The CAS Registry Mumber 9032-83-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 9,0,3 and 2 respectively; the second part has 2 digits, 8 and 3 respectively. Calculate Digit Verification of CAS Registry Number 9032-83: (6*9)+(5*0)+(4*3)+(3*2)+(2*8)+(1*3)=91 91 % 10 = 1 So 9032-83-1 is a valid CAS Registry Number.
9032-83-1Upstream product
9032-83-1Downstream Products
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